588-46-5, Adding some certain compound to certain chemical reactions, such as: 588-46-5, name is N-Benzylacetamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 588-46-5.
General procedure: Amide 1 (0.25 mmol, 1 equiv.) and Selectfluor (0.625 mmol, 2.5 equiv.) were dissolved in acetonitrile (5 mL) at room temperature, and CuBr (0.3 mmol, 1.2 equiv.) was added over a 40 min period in 6 portions. After all the CuBr was added, the resulting mixture was stirred for extra 20 min, and then acetonitrile was evaporated under reduced pressure. Saturated ammonium chloride solution (20 mL) was added into reaction mixture and extracted with diethyl ether (25 mL ¡Á 4); the ether layers were combined and dried over Na2SO4, filtered, evaporated under reduced pressure to give the crude product. Silica gel flash chromatography of the crude product [hexanes-ethyl acetate (10:1) to hexanes-ethyl acetate (4:1)] yielded pure imide 2.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 588-46-5.
Reference:
Article; Jin, Zhuang; Xu, Bo; Hammond, Gerald B.; Dimagno, Stephen G.; Journal of Fluorine Chemistry; vol. 143; (2012); p. 226 – 230,5;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics