Simple exploration of 144-80-9

The synthetic route of N-((4-Aminophenyl)sulfonyl)acetamide has been constantly updated, and we look forward to future research findings.

144-80-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 144-80-9, name is N-((4-Aminophenyl)sulfonyl)acetamide belongs to amides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

General procedure: A solution of 0.01 mol of methyl 4-(4-bromophenyl)-2,4-dioxobutanoate in 10 mL of glacial acetic acid was added to a solution of 0.01 mol of N-(4-aminobenzenesulfonyl)acetamide and 0.01 mol of benzaldehyde in 15 mL of glacial acetic acid. The mixture was refluxed for 3-5 min and cooled, and the precipitate was filtered off and recrystallized from dioxane [8]. Yield 4.33 g (78%).

The synthetic route of N-((4-Aminophenyl)sulfonyl)acetamide has been constantly updated, and we look forward to future research findings.

Reference:
Article; Bobrovskaya; Gein; Seliverstov; Chashchina; Dmitriev; Russian Journal of General Chemistry; vol. 87; 12; (2017); p. 2776 – 2782; Zh. Obshch. Khim.; vol. 87; 12; (2017); p. 1957 – 1964,8;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics