2895-21-8, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2895-21-8 as follows.
EXAMPLE 1 The compound N-isopropyl-alpha-chloroacetamide (2.71 g; 0.02 mole) and benzyltriethylammonium chloride (0.09 g) were dissolved in methylene chloride (50 ml) in a 100 ml flask. A 50% by weight sodium hydroxide solution (16 g) was added to the mixture, and the mixture was stirred vigorously at 40 C. for three days. Thereafter, the organic phase was separated, dried and evaporated. The residue of the evaporation (found to be four parts product per part starting material) was recrystallized from ethyl alcohol to yield 0.7 g (36%) of 1,4-diisopropyl-2,5-diketopiperazine. All spectral data were consistent with this structure.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2895-21-8, and friends who are interested can also refer to it.
Reference:
Patent; Monsanto Company; US4694082; (1987); A;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics