191170-76-0, The chemical industry reduces the impact on the environment during synthesis 191170-76-0, name is Benzyl 4-bromophenethylcarbamate, I believe this compound will play a more active role in future production and life.
A solution of H2SO4 (3 ml) and AcOH (6 mL) was cooled in an ice bath for 10 min. Paraformaldehyde (1.00 g, 33.3 mmol) and benzyl (4-bromophenethyl)carbamate (0.92 g, 2.75 mmol) were added to the cooled solution and the reaction was stirred for 10 min at 0 C, where upon the reaction was poured onto ice (ca. 50 g). When the ice melted, the aqueous solution was extracted with EtOAc (3 x 50 mL). The combined organic layers were washed with a saturated aqueous solution of NaHCCb (1 x 50 mL), water (1 x 50 mL), and brine (1 x 50 mL). The organic layer was dried (Na2S04) and concentrated under reduced pressure. The crude material was purified via flash column chromatography eluting with EtOAc:hexanes (5:95) to give 720 mg (76%) of title co s consistent with literature.1
The chemical industry reduces the impact on the environment during synthesis Benzyl 4-bromophenethylcarbamate. I believe this compound will play a more active role in future production and life.
Reference:
Patent; BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; MARTIN, Stephen, F.; SAHN, James, J.; LINKENS, Kathryn, Taylor; (119 pag.)WO2017/190109; (2017); A1;,
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