Adding a certain compound to certain chemical reactions, such as: 138-41-0, name is Carzenide, belongs to amides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 138-41-0, Application In Synthesis of Carzenide
Tolylsulfonamide 10 (1.00mM) was first converted to 4-aminosulfonyl benzoic acid by refluxing its aqueous suspension with KMnO4 (3.00mM) to generate the corresponding carboxylic acid followed by refluxing its methanolic solution firstly in acidic condition and then in excess of hydrazine hydrate.37 Yield 74%, lit. mp: 230-232C, Obs. mp: 228-230C.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Carzenide, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Sitaram; Celik, Gulsah; Khloya, Poonam; Vullo, Daniela; Supuran, Claudiu T.; Sharma, Pawan K.; Bioorganic and Medicinal Chemistry; vol. 22; 6; (2014); p. 1873 – 1882;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics