Electric Literature of 4943-86-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4943-86-6, name is 2-Amino-N-(4-chlorophenyl)benzamide, This compound has unique chemical properties. The synthetic route is as follows.
The reaction flask was added 1l (2mmol, 493mg),and then added tert-butyl nitrite (6mmol, 0.72mL),followed by tetrabutylammonium iodide (5mol%,37 mg of) and acetonitrile (20mL). Then the system was heated for 12 hours at 60 deg C. for air, vacuum spin dry acetateAfter the nitrile with petroleum ether / ethyl acetate = 6/1 mixed solvent of a simple column chromatography to give the product 2L, 86% yield. yellowsolid,
The chemical industry reduces the impact on the environment during synthesis 2-Amino-N-(4-chlorophenyl)benzamide. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Zhengzhou Institute of Light Industry; Yan, Yi zhe; Shi, Miao miao; Liu, Yan qi; Zhi, Huan huan; He, Yuan; Niu, Bin; (18 pag.)CN105418525; (2016); A;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics