Synthetic Route of 5680-80-8, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 5680-80-8, Name is H-Ser-OMe.HCl, SMILES is O=C(OC)[C@@H](N)CO.[H]Cl, belongs to amides-buliding-blocks compound. In a article, author is Kandler, Rene, introduce new discover of the category.
Synthesis and Fungicidal Activity of Novel Pyrazole-4-carbox-amide Compounds Containing Tertiary Alcohol Moiety
A series of novel pyrazole-4-carboxamide compounds were designed and synthesized through introducing a tertiary alcohol moiety into the C-3 position of the pyrazole ring based on the chracteristics of pyrazole-4-carboxamide fungicides and natural products with a tertiary alcohol moiety. Their structures were characterized by H-1 NMR, C-13 NMR, HR-ESI-MS data and X-ray diffraction. The preliminary bioassay results indicated that some of these compounds exhibit certain fungicidal activities against tested phytopathogens at the concentration of 100 mu g/mL. N-(2-Fluorophenyl)-3-(1-hydroxycyclohexyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide (B-1) and N-(thiazol-2-yl)-3-(1-hydroxycyclohexyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide (B-10) have EC50 values of 76.3 and 71.9 mu g/mL against Pythium aphanidermatum. B-10 has an EC50 value of 85.4 mu g/mL against Phytophthora capsici, respectively.
Synthetic Route of 5680-80-8, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 5680-80-8 is helpful to your research.