609-36-9, Name is H-DL-Pro-OH, molecular formula is C5H9NO2, belongs to amides-buliding-blocks compound, is a common compound. In a patnet, author is Sayes, Morgane, once mentioned the new application about 609-36-9, Recommanded Product: 609-36-9.
YEATS-domain-containing MLLT1 is an acetyl/aryl-lysine reader domain, which is structurally distinct from well-studied bromodomains and has been strongly associated in development of cancer. Here, we characterized piperazine-urea derivatives as an acetyl/acyl-lysine mimetic moiety for MLLT1. Crystal structures revealed distinct interaction mechanisms of this chemotype compared to the recently described benzimidazole-amide based inhibitors, exploiting different binding pockets within the protein. Thus, the piperazine-urea scaffold offers an alternative strategy for targeting the YEATS domain family.
If you’re interested in learning more about 609-36-9. The above is the message from the blog manager. Recommanded Product: 609-36-9.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics