Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Marshall, James R., once mentioned the application of 15761-38-3, Name is Boc-Ala-OH, molecular formula is C8H15NO4, molecular weight is 189.209, MDL number is MFCD00037225, category is amides-buliding-blocks. Now introduce a scientific discovery about this category, Formula: https://www.ambeed.com/products/15761-38-3.html.
A dehydroxylative Csp(3)-N coupling reaction assisted by triphenylphosphine has been developed through electrochemical oxidation. The reaction proceeds via anodic oxidation of triphenylphosphine to generate its corresponding radical cation, followed by reacting with hydroxyl groups to form alkoxy triphenylphosphonium ions, which are trapped by azoles or amides to construct C-N bonds. This method provides an efficient electrochemical strategy of activating hydroxyl groups to form C-N bonds under mild conditions.
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Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics