Reference of 5680-80-8, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 5680-80-8, Name is H-Ser-OMe.HCl, SMILES is O=C(OC)[C@@H](N)CO.[H]Cl, belongs to amides-buliding-blocks compound. In a article, author is Liu, Tie, introduce new discover of the category.
The synthesis, crystal structures, and reactivity of the most twisted acyclic amides described to date are reported. Substitution at the nitrogen atom in simple benzamides with Ts and acyl or carbamate groups provides a unique way to achieve almost perpendicular twist in N-acyclic amides (tau = 77 degrees, N = Ac; tau = 87 degrees, N = Boc). The overlap between the Nlp and CO pi* orbital is disrupted due to geometrical constraints around the N-substituents. The perpendicular acyclic twisted amides represent a transition state mimic of cis-trans peptide isomerization thus far only accessible by excessively twisted bridged lactams.
Reference of 5680-80-8, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 5680-80-8 is helpful to your research.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics