Chemistry, like all the natural sciences, Recommanded Product: 104-10-9, begins with the direct observation of nature— in this case, of matter.104-10-9, Name is 2-(4-Aminophenyl)ethanol, SMILES is NC1=CC=C(CCO)C=C1, belongs to amides-buliding-blocks compound. In a document, author is Navratil, Michal, introduce the new discover.
Aim: Highlighting the need for effective therapies for the treatment of ulcerative colitis, novel series of potential CB2 modulators (benzofuran and pyrrole carboxamides) were developed and tested for their functional activities on CB1/CB2 receptors. Results: In the benzofuran series, the cannabinoid (CB) receptor selectivity and the functional profile were dependent on the nature of the amide substituent and the position of the methoxy group, meanwhile the pyrrole derivatives, displayed an exclusive selectivity to the CB2 receptor and a functionality that is controlled by the nature of the pyrrole nitrogen substituent. Conclusion: Remarkably, we succeeded to develop potent and selective pyrrole-based CB2 receptor agonists, represented by compound 25a, which also demonstrated an exquisite anti-inflammatory effect in a dextran sodium sulfate-induced colitis model in mice.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 104-10-9. Recommanded Product: 104-10-9.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics