Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Zhang, Yan, once mentioned the application of 683-57-8, Name is 2-Bromoacetamide, molecular formula is C2H4BrNO, molecular weight is 137.9633, MDL number is MFCD00008025, category is amides-buliding-blocks. Now introduce a scientific discovery about this category, Quality Control of 2-Bromoacetamide.
A cantilever nanobiosensor functionalized with vegetable source of peroxidase was developed as an innovative way for glyphosate herbicide detection over a wide concentration range (0.01 to 10mgL(-1)) using atomic force microscopy (AFM) technique. The extract obtained from zucchini (Cucurbita pepo source of peroxidase), with high enzymatic activity and stability has been used as bio-recognition element to develop a nanobiosensor. The polarization-modulated reflection absorption infrared spectroscopy (PM-RAIRS) demonstrated the deposition of enzyme on cantilever surface using self-assembled monolayers (SAM) by the presence of the amide I and II bands. The detection mechanism of glyphosate was based on the changes in surface tension caused by the analyte adsorption, resulting in a conformational change in the enzyme structure. In this way, the results of nanobiosensor demonstrate the potential of the sensing device for detecting glyphosate with a detection limit of 0.028mgL(-1).
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Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics