I found the field of Pharmacology & Pharmacy very interesting. Saw the article Iodinated Choline Transport-Targeted Tracers published in 2020. Quality Control of 2-(4-Aminophenyl)ethanol, Reprint Addresses Hruby, M (corresponding author), CAS, Inst Macromol Chem, Prague 16206 6, Czech Republic.; Hajduch, M (corresponding author), Palacky Univ Olomouc, Fac Med & Dent, Inst Mol & Translat Med, Olomouc 77900, Czech Republic.. The CAS is 104-10-9. Through research, I have a further understanding and discovery of 2-(4-Aminophenyl)ethanol
We present a novel series of radioiodinated tracers and potential theranostics for diseases accompanied by pathological function of proteins involved in choline transport. Unlike choline analogues labeled with C-11 or F-18 that are currently used in the clinic, the iodinated compounds described herein are applicable in positron emission tomography, single-photon emission computed tomography, and potentially in therapy, depending on the iodine isotope selection. Moreover, favorable half-lives of iodine isotopes result in much less challenging synthesis by isotope exchange reaction. Six of the described compounds were nanomolar ligands, and the best compound possessed an affinity 100-fold greater than that of choline. Biodistribution data of I-125-labeled ligands in human prostate carcinoma bearing (PC-3) mice revealed two compounds with a biodistribution profile superior to that of [F-18]fluorocholine.
Quality Control of 2-(4-Aminophenyl)ethanol. About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Svec, P; Novy, Z; Kucka, J; Petrik, M; Sedlacek, O; Kuchar, M; Liskova, B; Medvedikova, M; Kolouchova, K; Groborz, O; Loukotova, L; Konefal, RL; Hajduch, M; Hruby, M or concate me.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics