Month: October 2021

In 2020.0 J ORGANOMET CHEM published article about RING-OPENING METATHESIS; PALLADIUM COMPLEXES; POLYMERIZATION; COPOLYMERIZATION; ETHYLENE; 1-ALKENE in [He, Xiaohui; Duan, Yapeng; Guo, Yan; Wang, Kai; Wu, Bin; Wen, Yufei; Zou, Jianhua; Zhu, Chuanyi; Huang, Shengmei] Nanchang Univ, Sch Mat Sci & Engn, 999 Xuefu Ave, Nanchang 330031, Jiangxi, Peoples R China; [Chen, Defu] Nanchang Univ, Sch Civil Engn & Architecture, 999 Xuefu Ave, Nanchang 330031, Jiangxi, Peoples R China; [Huang, Shengmei] Nanchang Hangkong Univ, Sch Mat Sci & Engn, Nanchang 330063, Jiangxi, Peoples R China in 2020.0, Cited 34.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Recommanded Product: 91-00-9

Three novel hexacoordinated nickel catalysts containing salicylaldbenzhydrylimine ligand and tetrahydrofuran heterocycle, Ni{(THF) (3-R-1) (5-R-2)C6H2(O)CHNCH(C6H5)(2)}(2), (R-1 = Br, R-2 = H, Ni1; R-1 = Br, R-2 = Br, Ni2; R-1 = Cl, R-2 = Cl, Ni3.), were synthesized and their molecular structures were confirmed by X-ray crystallography. Ni1-Ni3 catalysts exhibited high activities (0.53-2.11 x 10(6) g(polymer)/mol(Ni).h) toward norbornene homopolymerization and high activity (0.29-2.62 x 10(5) g(polymer)/mol(Ni).h) to copolymerization of norbornene and 1-hexene. When the 1-hexene feed ratio was changed from 10 to 70%, the 1-hexene content in the obtained copolymers could be controlled to 8.23-26.58%. The Ni3 with R-1 and R-2 were both electron withdrawing groups (-Cl) on the aromatic ring of salicylaldehyde, showed the highest activity as well as the highest 1-hexene insert ratios. At the same time, only a small amount of B(C6F5)(3) cocatalyst (5 x 10(-5) mol) need to be consumed in the copolymerization process. In addition, the obtained copolymers had a high thermal decomposition temperature (T-d > 386 degrees C) and a low glass transition temperature (T-g = 208.67-237.42 degrees C), which showed that the processability of these polymers was improved while the high thermal decomposition temperature was kept. The copolymers also exhibited good solubility in general organic solvents and high optical transparency in the visible region. (C) 2020 Elsevier B.V. All rights reserved.

Recommanded Product: 91-00-9. About Diphenylmethanamine, If you have any questions, you can contact He, XH; Duan, YP; Guo, Y; Wang, K; Wu, B; Wen, YF; Zou, JH; Zhu, CY; Huang, SM; Chen, DF or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

HPLC of Formula: C13H13N. Authors Ingale, AP; Ukale, D; Garad, DN; Shinde, SV in TAYLOR & FRANCIS INC published article about in [Ingale, Ajit P.] Savitribai Phule Pune Univ, Dada Patil Coll, Dept Chem, Ahmednagar, Maharashtra, India; [Ukale, Dattatraya] Univ Turku, Dept Chem, Turku, Finland; [Garad, Dnyaneshwar N.] Natl Univ Ireland Galway, Sch Chem, Galway, Ireland; [Shinde, Sandeep V.] Swami Ramanand Teerth Marathwada Univ, Pratibha Niketan Coll, Dept Chem, Nanded, India in 2021.0, Cited 17.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

Nanocerium oxide mediated an efficient and green protocol has been described for the chemoselective N-tert-butyloxycarbonylation of amines under the solvent-free conditions at ambient temperature. Various aliphatic, aromatic and heteroaromatic amines were protected using developed protocol and several functional groups such as alcohol, phenol and ester were well tolerated under these conditions. The rapid reaction rate, mild conditions, very good functional group tolerance, excellent yield, solvent-free, easy recovery products and excellent catalyst recyclability are the advantages of this protocol. This makes the protocol feasible, economical and environmentally benign.

HPLC of Formula: C13H13N. About Diphenylmethanamine, If you have any questions, you can contact Ingale, AP; Ukale, D; Garad, DN; Shinde, SV or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Quality Control of Benzo[d][1,2,3]triazin-4(3H)-one. In 2021 GREEN CHEM published article about ALKYNE INSERTION; LIGANDS; ACIDS; ANNULATION; 1,2,3-BENZOTRIAZIN-4(3H)-ONES in [Tang, Guo] Xiamen Univ, Dept Chem, Coll Chem & Chem Engn, Xiamen 361005, Fujian, Peoples R China; Xiamen Univ, Key Lab Chem Biol Fujian Prov, Xiamen 361005, Fujian, Peoples R China in 2021, Cited 54. The Name is Benzo[d][1,2,3]triazin-4(3H)-one. Through research, I have a further understanding and discovery of 90-16-4.

Metal-free, visible-light-induced denitrogenative phosphorylation of 1,2,3-benzotriazinones was achieved. With the use of eosin Y as a photoredox catalyst, N,N-diisopropylethylamine as a base, CH3CN-H2O as a solvent and sunlight or a blue LED as a light source, a variety of aryl-phosphonates, aryl-phosphinates, and aryl-phosphine oxides were efficiently prepared. In addition, B(2)pin(2) instead of P-nucleophiles as a radical acceptor was also demonstrated. The key advantages of this newly developed method are the clean reaction profile, use of a low-cost organic-dye catalyst, energy efficiency, broad substrate scope, good to excellent yields and large-scale synthetic applicability. The gram-scale synthesised compounds could be isolated in pure form just upon extraction, followed by re-crystallisation; no tedious chromatographic purification was required.

Quality Control of Benzo[d][1,2,3]triazin-4(3H)-one. About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact Chen, FS; Hu, SS; Li, SP; Tang, G; Zhao, YF or concate me.

Reference:
Patent; Guizhou University; Xue Wei; Zhang Juping; Zhang Cheng; Chen Lijuan; Wang Yihui; Li Pu; Li Qin; Ruan Xianghui; Wang Xiaobin; Wu Xiaoqiong; Wang Jun; (24 pag.)CN107602493; (2019); B;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Authors Xie, C; Song, JL; Wu, HR; Hu, Y; Liu, HZ; Zhang, ZR; Zhang, P; Chen, BF; Han, BX in AMER CHEMICAL SOC published article about HIGHLY EFFICIENT CATALYST; NITROGEN-COMPOUNDS; PRECIOUS-METAL; PRIMARY AMINES; KETO ACIDS; BIOMASS; HYDROGENATION; AMINATION/CYCLIZATION; HYDRODEOXYGENATION; TRANSFORMATION in [Xie, Chao; Song, Jinliang; Wu, Haoran; Hu, Yue; Liu, Huizhen; Zhang, Zhanrong; Zhang, Pei; Chen, Bingfeng; Han, Buxing] Chinese Acad Sci, Inst Chem, CAS Res Educ Ctr Excellence Mol Sci, Beijing Natl Lab Mol Sci,CAS Key Lab Colloid & In, Beijing 100190, Peoples R China; [Xie, Chao; Wu, Haoran; Hu, Yue; Liu, Huizhen; Han, Buxing] Univ Chinese Acad Sci, Sch Chem & Chem Engn, Beijing 100049, Peoples R China in 2019.0, Cited 50.0. Computed Properties of C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

Construction of N-substituted pyrrolidones from biomass-derived levulinic acid (LA) via reductive amination is a highly attractive route for biomass valorization. However, realizing this transformation using H-2 as the hydrogen source under mild conditions is still very challenging. Herein, we designed porous TiO2 nanosheets-supported Pt nanoparticles (Pt/P-TiO2) as the heterogeneous catalyst. The prepared Pt/P-TiO2 was highly efficient for reductive amination of LA to produce various N-substituted pyrrolidones (34 examples) at ambient temperature and H-2 pressure. Meanwhile, Pt/P-TiO2 showed good applicability for reductive amination of levulinic esters, 4-acetylbutyric acid, 2-acetylbenzoic acid, and 2-carboxybenzaldehyde. Systematic studies indicated that the strong acidity of P-TiO2 and the lower electron density of the Pt sites as well as the porous structure resulted in the excellent activity of Pt/P-TiO2.

Computed Properties of C13H13N. About Diphenylmethanamine, If you have any questions, you can contact Xie, C; Song, JL; Wu, HR; Hu, Y; Liu, HZ; Zhang, ZR; Zhang, P; Chen, BF; Han, BX or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

I found the field of Pharmacology & Pharmacy very interesting. Saw the article Iodinated Choline Transport-Targeted Tracers published in 2020. Quality Control of 2-(4-Aminophenyl)ethanol, Reprint Addresses Hruby, M (corresponding author), CAS, Inst Macromol Chem, Prague 16206 6, Czech Republic.; Hajduch, M (corresponding author), Palacky Univ Olomouc, Fac Med & Dent, Inst Mol & Translat Med, Olomouc 77900, Czech Republic.. The CAS is 104-10-9. Through research, I have a further understanding and discovery of 2-(4-Aminophenyl)ethanol

We present a novel series of radioiodinated tracers and potential theranostics for diseases accompanied by pathological function of proteins involved in choline transport. Unlike choline analogues labeled with C-11 or F-18 that are currently used in the clinic, the iodinated compounds described herein are applicable in positron emission tomography, single-photon emission computed tomography, and potentially in therapy, depending on the iodine isotope selection. Moreover, favorable half-lives of iodine isotopes result in much less challenging synthesis by isotope exchange reaction. Six of the described compounds were nanomolar ligands, and the best compound possessed an affinity 100-fold greater than that of choline. Biodistribution data of I-125-labeled ligands in human prostate carcinoma bearing (PC-3) mice revealed two compounds with a biodistribution profile superior to that of [F-18]fluorocholine.

Quality Control of 2-(4-Aminophenyl)ethanol. About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Svec, P; Novy, Z; Kucka, J; Petrik, M; Sedlacek, O; Kuchar, M; Liskova, B; Medvedikova, M; Kolouchova, K; Groborz, O; Loukotova, L; Konefal, RL; Hajduch, M; Hruby, M or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Authors Reddy, GS; Snehalatha, AV; Edwin, RK; Hossain, KA; Giliyaru, VB; Hariharapura, RC; Shenoy, GG; Misra, P; Pal, M in ACADEMIC PRESS INC ELSEVIER SCIENCE published article about 1,2,3-BENZOTRIAZIN-4-ONE DERIVATIVES; NEMATOCIDAL ACTIVITIES; INDOLES; 1-ALKYNES; RV1885C; 2-HETEROARYL; DOCKING; PROTEIN; 2-ARYL in [Reddy, Gangireddy Sujeevan; Snehalatha, Ampalam Venkata; Edwin, Rebecca Kristina; Hossain, Kazi Amirul; Misra, Parimal; Pal, Manojit] Dr Reddys Inst Life Sci, Univ Hyderabad Campus, Hyderabad 500046, India; [Reddy, Gangireddy Sujeevan; Giliyaru, Varadaraj Bhat; Hariharapura, Raghu Chandrashekhar; Shenoy, G. Gautham] Manipal Acad Higher Educ, Manipal Coll Pharmaceut Sci, Manipal 576104, Karnataka, India in 2019, Cited 38. HPLC of Formula: C7H5N3O. The Name is Benzo[d][1,2,3]triazin-4(3H)-one. Through research, I have a further understanding and discovery of 90-16-4

The chorismate mutase (CM) is considered as an attractive target for the identification of potential antitubercular agents due to its absence in animals but not in bacteria. A series of 3-indolylmethyl substituted pyrazolo-triazinone derivatives were designed and docked into CM in silico as potential inhibitors. These compounds were efficiently synthesized using the Pd/Cu-catalyzed coupling-cyclization in a single pot involving the construction of indole ring. The methodology was later extended to the preparation of corresponding benzo analogs of pyrazolotriazinones i.e. 3-indolylmethyl substituted benzotriazinone derivatives. Several of these novel compounds showed significant inhibition of CM when tested in vitro at 30 mu M. The SAR (Structure-Activity-Relationship) studies suggested that benzotriazinone moiety was more favorable over the pyrazolotriazinone ring. The two best active compounds showed IC50 similar to 0.4-0.9 mu M (better than the reference/known compounds used) and no toxicity till 30 mu M in vitro.

About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact Reddy, GS; Snehalatha, AV; Edwin, RK; Hossain, KA; Giliyaru, VB; Hariharapura, RC; Shenoy, GG; Misra, P; Pal, M or concate me.. HPLC of Formula: C7H5N3O

Reference:
Patent; Guizhou University; Xue Wei; Zhang Juping; Zhang Cheng; Chen Lijuan; Wang Yihui; Li Pu; Li Qin; Ruan Xianghui; Wang Xiaobin; Wu Xiaoqiong; Wang Jun; (24 pag.)CN107602493; (2019); B;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Asymmetric Hydrogenation of Dibenzo[c,e]azepine Derivatives with Chiral Cationic Ruthenium Diamine Catalysts published in 2019.0. Formula: C13H13N, Reprint Addresses Chen, F; Fan, QH (corresponding author), Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

An efficient Ru-catalyzed asymmetric hydrogenation of dibenzo[c,e]azepines is reported. A series of seven-membered cyclic amines were obtained with moderate to excellent enantioselectivity. The catalyst counteranion played an important role in achieving high-level chiral induction. Moreover, a one-pot synthesis of chiral 6,7-dihydro-5H-dibenz[c,e]azepines via two-step reductive amination was also developed.

Formula: C13H13N. About Diphenylmethanamine, If you have any questions, you can contact Zhang, SS; Chen, F; He, YM; Fan, QH or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Computed Properties of C13H13N. I found the field of Chemistry very interesting. Saw the article An Improved Synthesis of Urea Derivatives from N-Acylbenzotriazole via Curtius Rearrangement published in 2019, Reprint Addresses Tiwari, VK (corresponding author), Banaras Hindu Univ, Inst Sci, Dept Chem, Varanasi 22100, Uttar Pradesh, India.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine.

The good leaving tendency of the benzotriazole moiety has been exploited for the synthesis of symmetric, unsymmetric, N-acyl, and cyclic ureas in good yields from N-acylbenzotriazoles by treating the latter with various amines in the presence of TMSN N in a sealed tube. The salient features of the devised protocol includes the high-yield, mild, metal-free, one-pot reaction conditions, and short reaction time. Furthermore, in many cases, no column chromatography is required for the purification.

About Diphenylmethanamine, If you have any questions, you can contact Singh, AS; Agrahari, AK; Singh, SK; Yadav, MS; Tiwari, VK or concate me.. Computed Properties of C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Meng, GY; Guo, TJ; Ma, TC; Zhang, J; Shen, YC; Sharpless, KB; Dong, JJ in [Meng, Genyi; Guo, Taijie; Ma, Tiancheng; Zhang, Jiong; Shen, Yucheng; Sharpless, Karl Barry; Dong, Jiajia] Univ Chinese Acad Sci, Ctr Excellence Mol Synth, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem,Chinese Acad Sci, Shanghai, Peoples R China published Modular click chemistry libraries for functional screens using a diazotizing reagent in 2019, Cited 33. Product Details of 91-00-9. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Click chemistry is a concept in which modular synthesis is used to rapidly find new molecules with desirable properties(1). Copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) triazole annulation and sulfur(VI) fluoride exchange (SuFEx) catalysis are widely regarded as click reactions(2-4), providing rapid access to their products in yields approaching 100% while being largely orthogonal to other reactions. However, in the case of CuAAC reactions, the availability of azide reagents is limited owing to their potential toxicity and the risk of explosion involved in their preparation. Here we report another reaction to add to the click reaction family: the formation of azides from primary amines, one of the most abundant functional groups(5). The reaction uses just one equivalent of a simple diazotizing species, fluorosulfuryl azide(6-11) (FSO2N3), and enables the preparation of over 1,200 azides on 96-well plates in a safe and practical manner. This reliable transformation is a powerful tool for the CuAAC triazole annulation, the most widely used click reaction at present. This method greatly expands the number of accessible azides and 1,2,3-triazoles and, given the ubiquity of the CuAAC reaction, it should find application in organic synthesis, medicinal chemistry, chemical biology and materials science.

About Diphenylmethanamine, If you have any questions, you can contact Meng, GY; Guo, TJ; Ma, TC; Zhang, J; Shen, YC; Sharpless, KB; Dong, JJ or concate me.. Product Details of 91-00-9

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Synthesis of 3-indolylmethyl substituted (pyrazolo/benzo)triazinone derivatives under Pd/Cu-catalysis: Identification of potent inhibitors of chorismate mutase (CM) WOS:000487812000051 published article about 1,2,3-BENZOTRIAZIN-4-ONE DERIVATIVES; NEMATOCIDAL ACTIVITIES; INDOLES; 1-ALKYNES; RV1885C; 2-HETEROARYL; DOCKING; PROTEIN; 2-ARYL in [Reddy, Gangireddy Sujeevan; Snehalatha, Ampalam Venkata; Edwin, Rebecca Kristina; Hossain, Kazi Amirul; Misra, Parimal; Pal, Manojit] Dr Reddys Inst Life Sci, Univ Hyderabad Campus, Hyderabad 500046, India; [Reddy, Gangireddy Sujeevan; Giliyaru, Varadaraj Bhat; Hariharapura, Raghu Chandrashekhar; Shenoy, G. Gautham] Manipal Acad Higher Educ, Manipal Coll Pharmaceut Sci, Manipal 576104, Karnataka, India in 2019, Cited 38. Recommanded Product: Benzo[d][1,2,3]triazin-4(3H)-one. The Name is Benzo[d][1,2,3]triazin-4(3H)-one. Through research, I have a further understanding and discovery of 90-16-4

The chorismate mutase (CM) is considered as an attractive target for the identification of potential antitubercular agents due to its absence in animals but not in bacteria. A series of 3-indolylmethyl substituted pyrazolo-triazinone derivatives were designed and docked into CM in silico as potential inhibitors. These compounds were efficiently synthesized using the Pd/Cu-catalyzed coupling-cyclization in a single pot involving the construction of indole ring. The methodology was later extended to the preparation of corresponding benzo analogs of pyrazolotriazinones i.e. 3-indolylmethyl substituted benzotriazinone derivatives. Several of these novel compounds showed significant inhibition of CM when tested in vitro at 30 mu M. The SAR (Structure-Activity-Relationship) studies suggested that benzotriazinone moiety was more favorable over the pyrazolotriazinone ring. The two best active compounds showed IC50 similar to 0.4-0.9 mu M (better than the reference/known compounds used) and no toxicity till 30 mu M in vitro.

Recommanded Product: Benzo[d][1,2,3]triazin-4(3H)-one. About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact Reddy, GS; Snehalatha, AV; Edwin, RK; Hossain, KA; Giliyaru, VB; Hariharapura, RC; Shenoy, GG; Misra, P; Pal, M or concate me.

Reference:
Patent; Guizhou University; Xue Wei; Zhang Juping; Zhang Cheng; Chen Lijuan; Wang Yihui; Li Pu; Li Qin; Ruan Xianghui; Wang Xiaobin; Wu Xiaoqiong; Wang Jun; (24 pag.)CN107602493; (2019); B;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics