Tamura, S; Sugawara, A; Sato, E; Sato, F; Sato, K; Kawano, T in [Tamura, Satoru; Sugawara, Aoi; Sato, Erika; Sato, Fuka; Sato, Keigo; Kawano, Tomikazu] Iwate Med Univ, Sch Pharm, Dept Med & Organ Chem, Yahaba, Iwate 0283694, Japan published New approach for induction of alkyl moiety to aliphatic amines by NaBH(OAc)(3) with carboxylic acid in 2020.0, Cited 13.0. SDS of cas: 91-00-9. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.
We had found the novel N-alkylation method, which utilizes carboxylic acids as alkyl sources with sodium triacetoxyborohydride [NaBH(OAc)(3)]. Our methodology had been revealed to have some advantages over the reported similar procedures. Through the further investigation about our method, it was disclosed that acetonitrile was the suitable solvent and N-alkylation for aliphatic amines were also smoothly proceeded. On the way of the research, we discovered that 4-hydroxybutyl moiety was induced to aniline by use of old THF containing peroxidic materials. (C) 2020 Elsevier Ltd. All rights reserved.
Welcome to talk about 91-00-9, If you have any questions, you can contact Tamura, S; Sugawara, A; Sato, E; Sato, F; Sato, K; Kawano, T or send Email.. SDS of cas: 91-00-9
Reference:
Amide – Wikipedia,
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