So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Levkovskaya, G. G.; Bozhenkov, G. V.; Malyushenko, R. N.; Mirskova, A. N. researched the compound: 3-(Chloromethyl)-1-methyl-1H-pyrazole( cas:84547-64-8 ).Safety of 3-(Chloromethyl)-1-methyl-1H-pyrazole.They published the article 《Synthesis of pyrazole derivatives from 1,1-dimethylhydrazine and chlorovinyl ketones》 about this compound( cas:84547-64-8 ) in Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). Keywords: chlorovinyl ketone cyclization methylhydrazine; pyrazol preparation; hydrazinium methyl chloride preparation. We’ll tell you more about this compound (cas:84547-64-8).
The reaction of accessible 2-chlorovinyl Me ketones with 1,1-dimethylhydrazine gave pyrazole derivatives in high yields. 1,1,1-Trimethylhydrazinium chloride was isolated as second product of this reaction in high yield.
As far as I know, this compound(84547-64-8)Safety of 3-(Chloromethyl)-1-methyl-1H-pyrazole can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics