Levkovskaya, G. G.; Bozhenkov, G. V.; Larina, L. I.; Mirskova, A. N. published the article 《New synthesis and properties of 3-alkyl-, 3-chloroalkyl-, 3-perfluoroalkyl-, and 3-aryl-1-methyl-5-halopyrazoles from chloro(bromo)vinyl ketones and N,N-dimethylhydrazine》. Keywords: regioselective heterocyclization halovinyl ketone dimethylhydrazine; halopyrazole preparation; pyrazole halo preparation.They researched the compound: 3-(Chloromethyl)-1-methyl-1H-pyrazole( cas:84547-64-8 ).Electric Literature of C5H7ClN2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:84547-64-8) here.
A new regioselective heterocyclization was revealed in the reaction of 2-chloro- and 2,2-dichloro(bromo)vinyl ketones with N,N-dimethylhydrazine to afford 3-substituted 1-methyl-5-halopyrazoles. The reaction is accompanied by elimination of Me halide and formation of up to 90% of N,N,N-trimethylhydrazinium halide as the second product.
This literature about this compound(84547-64-8)Electric Literature of C5H7ClN2has given us a lot of inspiration, and I hope that the research on this compound(3-(Chloromethyl)-1-methyl-1H-pyrazole) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics