The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3-(Chloromethyl)-1-methyl-1H-pyrazole( cas:84547-64-8 ) is researched.Electric Literature of C5H7ClN2.Levkovskaya, G. G.; Bozhenkov, G. V.; Malyushenko, R. N.; Mirskova, A. N. published the article 《Synthesis of pyrazole derivatives from 1,1-dimethylhydrazine and chlorovinyl ketones》 about this compound( cas:84547-64-8 ) in Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). Keywords: chlorovinyl ketone cyclization methylhydrazine; pyrazol preparation; hydrazinium methyl chloride preparation. Let’s learn more about this compound (cas:84547-64-8).
The reaction of accessible 2-chlorovinyl Me ketones with 1,1-dimethylhydrazine gave pyrazole derivatives in high yields. 1,1,1-Trimethylhydrazinium chloride was isolated as second product of this reaction in high yield.
When you point to this article, it is believed that you are also very interested in this compound(84547-64-8)Electric Literature of C5H7ClN2 and due to space limitations, I can only present the most important information.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics