The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 3-(Chloromethyl)-1-methyl-1H-pyrazole, is researched, Molecular C5H7ClN2, CAS is 84547-64-8, about Synthesis of new proton-pump inhibitors (2) and tests for it’s biological activity, the main research direction is antiulcer agent omeprazole analog preparation.Formula: C5H7ClN2.
For development new anti-ulcer agents, we synthesized proton-pump (H+/K+-ATPase) inhibitors which inhibit gastric acid secretion at the last step in the parietal cell. These are omeprazole analogs, in which pyridine group is replaced by pyrazole moiety, to increase pharmacol. activity and to decrease side effects, and we also synthesized substituted benzimidazole rings. The structure of the compounds was identified with 1H-NMR, M.S. and I.R. The compounds with 5-substituted benzimidazoles showed good activity in the following order MeO > Cl > H, and also, 1-benzyl group of pyrazole substituted compounds has enhanced activity.
This literature about this compound(84547-64-8)Formula: C5H7ClN2has given us a lot of inspiration, and I hope that the research on this compound(3-(Chloromethyl)-1-methyl-1H-pyrazole) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics