Qiao, Jin-Bao; Zhang, Ya-Qian; Yao, Qi-Wei; Zhao, Zhen-Zhen; Peng, Xuejing; Shu, Xing-Zhong published the artcile< Enantioselective Reductive Divinylation of Unactivated Alkenes by Nickel-Catalyzed Cyclization-Coupling Reaction>, Computed Properties of 1524-40-9, the main research area is methylene five membered heterocycle carbocycle chemoselective regioselective enantioselective preparation; bromo diene vinyl electrophile divinylation cyclization coupling nickel catalyst.
An enantioselective cross-electrophile divinylation reaction of nonaromatic substrates, 2-bromo-1,6-dienes was reported. The approach thus offered a route to new chiral cyclic architectures, which were key structural motifs found in various biol. active compounds The reaction proceeded under mild conditions, and use of chiral t-Bu-pmrox and 3,5-difluoro-pyrox ligands resulted in formation of divinylated products with high chemo-, regio-, and enantioselectivity. The method was applicable for incorporation of chiral hetero- and carbocycles into complex mols.
Journal of the American Chemical Society published new progress about Alkadienes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1524-40-9 belongs to class amides-buliding-blocks, and the molecular formula is C6H6FNO2S, Computed Properties of 1524-40-9.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics