In 2019,Angewandte Chemie, International Edition included an article by Berthold, Dino; Geissler, Arne G. A.; Giofre, Sabrina; Breit, Bernhard. Recommanded Product: 70-55-3. The article was titled 《Rhodium-Catalyzed Asymmetric Intramolecular Hydroamination of Allenes》. The information in the text is summarized as follows:
The rhodium-catalyzed asym. intramol. hydroamination of sulfonyl amides with terminal allenes was reported. It provided selective access to 5- and 6-membered N-heterocycles, scaffolds found in a large range of different bioactive compounds Moreover, gram scale reactions, as well as the application of suitable product transformations to natural products and key intermediates thereof were demonstrated. The results came from multiple reactions, including the reaction of 4-Methylbenzenesulfonamide(cas: 70-55-3Recommanded Product: 70-55-3)
4-Methylbenzenesulfonamide(cas: 70-55-3) belongs to anime. Amines characteristically form salts with acids; a hydrogen ion, H+, adds to the nitrogen. With the strong mineral acids (e.g., H2SO4, HNO3, and HCl), the reaction is vigorous. Salt formation is instantly reversed by strong bases such as NaOH. Neutral electrophiles (compounds attracted to regions of negative charge) also react with amines; alkyl halides (R′X) and analogous alkylating agents are important examples of electrophilic reagents.Recommanded Product: 70-55-3
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics