SDS of cas: 70-55-3In 2020 ,《Highly Regio-, Diastereo- and Enantioselective Synthesis of Tetrahydroazepines and Benzo[b]oxepines through Palladium-Catalyzed [4+3] Cycloaddition Reactions》 was published in Angewandte Chemie, International Edition. The article was written by Trost, Barry M.; Zuo, Zhijun. The article contains the following contents:
A novel Pd0-catalyzed asym. [4+3] annulation reaction of two readily accessible starting materials was developed for building seven-membered heterocyclic architectures. The potential [3+2] side pathway could be suppressed though fine tuning of the conditions. A broad scope of cycloaddition donors and acceptors participated in the transformation with excellent chemo-, regio-, diastereo- and enantioselectivtities, leading to valuable tetrahydroazepines, e.g., I and benzo[b]oxepines, e.g., II. In addition to this study using 4-Methylbenzenesulfonamide, there are many other studies that have used 4-Methylbenzenesulfonamide(cas: 70-55-3SDS of cas: 70-55-3) was used in this study.
4-Methylbenzenesulfonamide(cas: 70-55-3) belongs to anime. Left-handed and right-handed forms (mirror-image configurations, known as optical isomers or enantiomers) are possible when all the substituents on the central nitrogen atom are different (i.e., the nitrogen is chiral). With amines, there is extremely rapid inversion in which the two configurations are interconverted.SDS of cas: 70-55-3
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics