Khalaj, A.’s team published research in Synthesis in 1985 | CAS: 4746-61-6

2-Hydroxy-N-phenylacetamide(cas: 4746-61-6) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors.SDS of cas: 4746-61-6 In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well.

Khalaj, A.; Nahid, E. published their research in Synthesis on December 31 ,1985. The article was titled 《Synthesis of α-hydroxy carboxamides from acetonides of α-hydroxy carboxylic acids and primary amines》.SDS of cas: 4746-61-6 The article contains the following contents:

Acetonides I (R = H, Me, Ph; R1 = H, Ph) were treated with R2NH2 (R2 = Pr, Ph, 4-O2NC6H4, 2-pyridyl) to give 30-78% HOCRR1CONHR2 (13 compounds). The reactions were performed by heating in a H2O bath without solvent, in refluxing C6H6 or PhMe or in xylene in a sealed tube at 200°. The experimental process involved the reaction of 2-Hydroxy-N-phenylacetamide(cas: 4746-61-6SDS of cas: 4746-61-6)

2-Hydroxy-N-phenylacetamide(cas: 4746-61-6) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors.SDS of cas: 4746-61-6 In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics