《Investigation of kinetics and mechanistic studies of N-(2-hydroxyethyl)phthalimide by +1 halogen oxidant in acidic medium》 was written by Latha, Vijaya; Sukhdev, Anu; Manjunath, A. S.; Puttaswamy; Deepthi, P. R.; Kumar, P. Mohan. Recommanded Product: 4-Methylbenzenesulfonamide And the article was included in Chemical Data Collections in 2020. The article conveys some information:
The oxidation of N-(2-hydroxyethyl)phthalimide (NHEP) by chloramine T (CAT) in perchloric acid medium has been investigated iodometrically at 298 K. The stoichiometry of the reaction was found to be 1:2. The oxidation products were identified by LC-MS anal. Kinetic orders with respect to oxidant, substrate and acid concentrations were determined Enhancement of rate observed with an increase in acid concentration Effect of solvent polarity and ionic strength was studied. Addition of p-toluene sulfonamide (reductant) to the reaction mixture has no significant influence on the rate. The active species of the oxidant in acidic medium was ascertained. Plausible mechanistic scheme explaining all of the observed kinetic results have been proposed. The effect of temperature on the reaction rates has also been studied. Activation parameters and thermodn. quantities were evaluated and discussed. The rate constant of the slow step of the reaction along with the equilibrium constants were also calculated The experimental part of the paper was very detailed, including the reaction process of 4-Methylbenzenesulfonamide(cas: 70-55-3Recommanded Product: 4-Methylbenzenesulfonamide)
4-Methylbenzenesulfonamide(cas: 70-55-3) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHR′) to form imines (R2C=NR′). Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.Recommanded Product: 4-Methylbenzenesulfonamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics