Nguyen, Trang T.; Hull, Kami L. published their research in ACS Catalysis on December 2 ,2016. The article was titled 《Rhodium-Catalyzed Oxidative Amidation of Sterically Hindered Aldehydes and Alcohols》.Related Products of 70298-88-3 The article contains the following contents:
In the presence of Rh(cod)2BF4, either 1,4-bis(diphenylphosphino)butane, tricyclohexylphosphine, or Xantphos, and either styrene, Me methacrylate, or α,α,α-trifluoroacetophenone with cesium acetate in THF, pivaldehyde or β,β-disubstituted alcs. underwent oxidative amidation with aliphatic and aromatic amines to yield hindered α,α-disubstituted amides in 25-94% yields. Mechanistic studies were performed to gain insight into the catalytic cycles for aldehyde and alc. amidation. The results came from multiple reactions, including the reaction of 2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3Related Products of 70298-88-3)
2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Related Products of 70298-88-3
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics