On June 30, 2015, Suhasini, K. P.; Christopher, V.; Kumar, Ch. Praveen; Rao, S. Rama Mohana; Murthy, Y. L. N. published an article.Safety of 2-(4-Methylbenzamido)acetic acid The title of the article was Synthesis, characterisation and antimycobacterial screening of 5(4H)-oxazolone derivatives against M. tuberculosis H37Rv. And the article contained the following:
A series of 4-(substituted benzylidene)-2-p-tolyloxazol-5(4H)-ones I [R = H, 4-Cl, 2,5-(OCH3)2, etc.] has been designed, synthesized and subjected to evaluate their antimycobacterial activity against Mycobacterium tuberculosis H37Rv in comparison with standard drugs Rifampicin and Isoniazid. The out-put of these studies disclosed that all the synthesized target mols. of the series displayed good to moderate activity with MIC values ranging 8-64 U+03BCg/mL. The compound I [R = 2,4,6-(OCH3)3] is the most distinctive compound identified, amongst the series because of its remarkable in vitro antimycobacterial activity and thus may act as a promising lead mol. for further explorations. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Safety of 2-(4-Methylbenzamido)acetic acid
The Article related to oxazolone preparation antimycobacterial, methylbenzamido acetic acid preparation aldehyde aryl erlenmeyer plochl azlactone, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.Safety of 2-(4-Methylbenzamido)acetic acid
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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics