Ingemann, M.’s team published research in Proceedings of the International Symposium on Controlled Release of Bioactive Materials in 1997 | CAS: 10405-38-6

Proceedings of the International Symposium on Controlled Release of Bioactive Materials published new progress about Oral drug delivery systems. 10405-38-6 belongs to class amides-buliding-blocks, name is N,N’-(Butane-1,4-diyl)diacrylamide, and the molecular formula is C10H16N2O2, Product Details of C10H16N2O2.

Ingemann, M. published the artcileStability of enzymes formulated for oral drug delivery, Product Details of C10H16N2O2, the main research area is oral drug delivery enzyme stability.

An oral drug delivery system based on entrapment of an enzyme of interest in acrylic hydrogel is, from a stability point of view, possible for lipase but not for phenylalanine ammonia lyase (PAL). Loss in enzymic activity, when monomers were present, may be caused by conformational changes in the PAL mol. as indicated in CD and fluorescence anal. It was shown that the proteolytic stability of free enzymes has to be improved by the aid of a drug delivery system before oral enzyme substitution therapy by PAL is possible.

Proceedings of the International Symposium on Controlled Release of Bioactive Materials published new progress about Oral drug delivery systems. 10405-38-6 belongs to class amides-buliding-blocks, name is N,N’-(Butane-1,4-diyl)diacrylamide, and the molecular formula is C10H16N2O2, Product Details of C10H16N2O2.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics