Ma, Peng-Ju published the artcileAddition-Rearrangement of Ketenes with Lithium N-tert-Butanesulfinamides: Enantioselective Synthesis of α,α-Disubstituted α-Hydroxycarboxylic Acid Derivatives, Synthetic Route of 343338-28-3, the main research area is hydroxycarboxamide enantioselective preparation; nonracemic sulfonamide lithiation stereoselective addition ketene rearrangement; tandem stereoselective addition sulfinamide ketene rearrangement.
Addition of the lithium salts of nonracemic sulfinamides such as I (generated in situ) to ketenes such as PhEtC:C:O (either prepared or generated in situ from the corresponding acyl chlorides) followed by Mislow-Evans [2,3]-sigmatropic rearrangement yielded sulfenates of α-hydroxycarboxamides such as II; the absolute stereochem. of the sulfinamide was transferred to the new stereocenter with high fidelity.
Organic Letters published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Synthetic Route of 343338-28-3.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics