Ramaiah, Manjunatha M. published the artcile1,8-Diazabicyclo[5.4.0]undec-7-ene-mediated formation of N-sulfinyl imines, Application of (S)-2-Methylpropane-2-sulfinamide, the main research area is sulfinyl imine preparation; tert butanesulfinamide aldehyde para toluenesulfinamide condensation DBU mediated; para toluenesulfinamide alc tert butanesulfinamide condensation DBU mediated.
A facile and efficient method was developed for the preparation of a variety of aryl, heteroaryl, and alkyl N-sulfinyl imines RCH=NS(O)R1 [R = cyclopropyl, 2-FC6H4, 8-quinolinyl, etc.; R1 = tBu, 4-MeC6H4; stereo = (S)] using 1,8-diazabicyclo[5.4.0]undec-7-ene. In addition to tert-butanesulfinamide, the condensation was also effective with p-toluenesulfinamide. The reaction was performed at room temperature and produced corresponding N-sulfinyl imines RCH=NS(O)R1 in excellent yields in absence of acids, metals, and additives. This methodol. was also useful for the preparation of N-sulfinyl imines on gram scale. A one-pot synthesis was developed using aryl and heteroaryl alcs. with both tert-butanesulfinamide and p-toluenesulfinamide at room temperature, resulting in corresponding N-sulfinyl imines with good yields.
Journal of Chemical Research published new progress about Alcohols, unsaturated Role: RCT (Reactant), RACT (Reactant or Reagent). 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Application of (S)-2-Methylpropane-2-sulfinamide.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics