Sharma, Hayden A. published the artcileEnantioselective catalytic 1,2-boronate rearrangements, Quality Control of 343338-28-3, the main research area is enantioselective boronate rearrangement boronic ester dichloromethane lithium ureaboronate catalyst; lithium urea boronate complex preparation catalyst boronate rearrangement dichloromethane; crystal structure lithium urea boronate complex; mol structure lithium urea boronate complex.
A strategy that facilitates the construction of a wide variety of trisubstituted stereocenters through a catalytically accessed common chiral intermediate could prove highly enabling for the field of synthetic chem. The authors report the discovery of enantioselective, catalytic 1,2-boronate rearrangements for the synthesis of α-chloro pinacol boronic esters from readily available boronic esters and CH2Cl2. The chiral building blocks produced in these reactions can undergo two sequential stereospecific elaborations to generate a wide assortment of trisubstituted stereocenters. The enantioselective reaction is catalyzed by a Li-isothiourea-boronate complex, which is proposed to promote rearrangement through a dual-Li-induced chloride abstraction orchestrated by Lewis basic functionality on the catalyst scaffold.
Science (Washington, DC, United States) published new progress about Addition reaction catalysts (Li-isothiourea-boronate complex). 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Quality Control of 343338-28-3.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics