Zhang, Pei-Chao published the artcilePd/PC-Phos-Catalyzed Enantioselective Intermolecular Denitrogenative Cyclization of Benzotriazoles with Allenes and N-Allenamides, Name: (S)-2-Methylpropane-2-sulfinamide, the main research area is regioselective enantioselective intermol denitrogenative cyclization benzotriazole allene allenamide; palladium sulfinamide phosphine catalyzed cyclization methyleneindoline preparation; allenamides; allenes; cyclization; heterocycles; palladium.
Reported herein is an asym. Pd/PC-Phos-catalyzed denitrogenative cyclization of benzotriazoles with allenes and N-allenamides, representing the first example of enantioselective denitrogenative cyclizations of benzotriazoles. A series of optically active 3-methyleneindolines were obtained in good yields with high ee values. The use of inexpensive and readily available starting materials, high regio- and enantioselectivity, a broad substrate scope, mild reaction conditions, no need for base, as well as versatile functionalization of the 3-methyleneindolines make this approach attractive.
Angewandte Chemie, International Edition published new progress about Allenes Role: RCT (Reactant), RACT (Reactant or Reagent). 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Name: (S)-2-Methylpropane-2-sulfinamide.
Referemce:
Amide – Wikipedia,
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