Madron du Vigne, Adrien published the artcileChiral Cyclic Alkyl Amino Carbene (CAAC) Transition-Metal Complexes: Synthesis, Structural Analysis, and Evaluation in Asymmetric Catalysis, HPLC of Formula: 343338-28-3, the main research area is chiral cyclic alkyl amino carbene CAAC transition metal complex; asym catalysis chiral cyclic alkyl amino carbene transition metal; conjugate borylation asym alpha beta unsaturated ester copper carbene; crystal mol structure cyclic alkyl amino carbene transition metal.
Despite recent advances in the field of cyclic alkyl amino carbenes (CAACs) including a few complementary synthetic strategies affording CAACs with various substitution patterns, the application potential of chiral CAACs to efficiently catalyze asym. organometallic transformations remains largely underdeveloped. Herein, authors describe a convenient and robust route that incorporates common chiral primary amine allowing access of a broad range of chiral CAACs precursors. The corresponding transition-metal complexes with Cu, Au, Ru, Rh, Ir, and Pd were obtained in a straightforward manner. The steric parameters of the complexes were comprehensively collected by x-ray single-crystal anal. to serve as a source of information for further ligand design. The preliminary application potential of the copper CAAC complexes was tested in asym. conjugate borylation of an α,β-unsaturated ester providing 89:11 er, thus illustrating the potential of chiral CAACs in asym. catalysis.
Organometallics published new progress about Borylation (asym. conjugate). 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, HPLC of Formula: 343338-28-3.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics