You, Ge-Yun published the artcileSimple chiral sulfinyl imine-thioether ligands for Pd-catalyzed allylic alkylation, Quality Control of 343338-28-3, the main research area is chiral sulfnyl imine thioether ligand preparation; diester biphenyl allylacetate palladium sulfnyl iminethioether catalyst allylic alkylation; biphenyl allyl ester enantioselective preparation.
A set of chiral sulfinyl imine-thioether ligands were prepared via dehydration condensation of substituted benzaldehyde and chiral sulfinamide. The activity of these ligands in Pd-catalyzed asym. allylic alkylation reaction was studied, and the results indicate that the structure of sulfinamide motifs has an obvious effect on the e.r. value and yield. The chiral p-tolylsulfinamide derived ligands can promote the reaction efficiently, while the ligands with tert-Bu group fail to catalyze the reaction. Then, the substrate scope was also investigated under the optimal reaction conditions.
Chemical Papers published new progress about Allylic alkylation catalysts, stereoselective. 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Quality Control of 343338-28-3.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics