Chen, Wen published the artcileTotal synthesis of (-)-vindoline, Name: (S)-2-Methylpropane-2-sulfinamide, the main research area is vindoline synthesis.
In this full paper, a stereocontrolled strategy for the total synthesis of (-)-vindoline is described. This synthetic route features: (1) rapid construction of the stereochem. center at C19 through a highly diastereoselective vinylogous Mannich addition; (2) tandem Heathcock/aza-Prins cyclization to install rings C and E in vindoline; (3) oxidative transformation of β-ketoester to enone; (4) stereoselective inversion of C4 stereochem. with triphenylphosphine and carbon tetrabromide followed by Bronsted acid.
Tetrahedron published new progress about Cyclization. 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Name: (S)-2-Methylpropane-2-sulfinamide.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics