Accelerated stability and chemical kinetics of ethanol extracts of fruit of Piper sarmentosum using high performance liquid chromatography was written by Khalid, Hussain;Zhari, Ismail;Amirin, Sadikun;Pazilah, Ibrahim. And the article was included in Iranian Journal of Pharmaceutical Research in 2011.HPLC of Formula: 18836-52-7 The following contents are mentioned in the article:
The extracts of Piper sarmentosum, a medicinal plant, are being used to prepare phytopharmaceuticals while the information about chem. kinetics of constituents of the extract is unavailable to assign precise shelf life (t90) and find optimum storage conditions of the product for patient safety, and to avoid economic repercussions of launching an unstable product. The extract was exposed to three different conditions of high temperature and relative humidity (RH) for six months. The samples were then analyzed at 0, 1, 2, 4 and 6 mo by high performance liquid chromatog. (HPLC) using pellitorine, sarmentine and sarmentosine as markers. Different chem. kinetic parameters of the markers were evaluated by Arrhenius equation to predict shelf life (t90) at different storage conditions and at room temperature The markers in the extract followed the zero order degradation, and the activation energy, pre exponential factor and rate constant of the reaction of the markers were found to be varying in samples stored at different conditions. The contents of the markers were found to be decreasing at high temperature and humidity with the passage of time. The predicted shelf life (t90) of the markers at room temperature was found to be 16 mo approx. Results of this study indicate that extracts of the plant are stable at room temperature for 16 mo. Moreover, the chem. kinetic data of the markers and the anal. method used to quantify the markers may be useful for phytopharmaceutical industry to produce efficacious and stable products from extracts of the plant. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7HPLC of Formula: 18836-52-7).
(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.HPLC of Formula: 18836-52-7
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics