Wong, Anthony published the artcileTissue-Reparative Benefits of MST1/2 Inhibition: Separating the Wheat From the Chaff, Product Details of C12H23N3S, the publication is Circulation Research (2021), 129(10), 927-929, database is CAplus and MEDLINE.
Identifying potential therapeutic targets for tissue repair following injury such as myocardial infarction (Ml) is a difficult task given the need to maintain the temporal balance of acute inflammation and resolution post-MI. Using XMU-MP-1 to inhibit MST1/2 activity, they found increased tissue fibrosis, left ventricular dilation, tissue fibrosis, inflammatory cytokine production, mortality, and decreased cardiac function. Importantly, pharmacol. inhibition of LTB4 alone had no effect, but when combined with XMU-MP-1 treatment, blockade of both MST1/2 and LTB4 ameliorated cardiac function and adverse tissue remodeling post-MI.
Circulation Research published new progress about 321673-30-7. 321673-30-7 belongs to amides-buliding-blocks, auxiliary class Immunology/Inflammation,Scavenger receptor, name is [(2-Hexylcyclopentylidene)amino]thiourea, and the molecular formula is C13H14BNO2, Product Details of C12H23N3S.
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https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics