Cotinguiba, Fernando et al. published their research in Medicinal Chemistry Research in 2009 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Piperamides and their derivatives as potential anti-trypanosomal agents was written by Cotinguiba, Fernando;Regasini, Luis Octavio;Bolzani, Vanderlan da Silva;Debonsi, Hosana Maria;Duo Passerini, Gabriela;Cicarelli, Regina Maria Barretto;Kato, Massuo Jorge;Furlan, Maysa. And the article was included in Medicinal Chemistry Research in 2009.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

We describe herein an evaluation of the trypanocidal effect of eight piperamides (1-8) isolated from Pipertuberculatum bearing dihydropyridone, piperidine, and iso-Bu moieties against epimastigote forms of Trypanosoma cruzi, the causative agent of Chagas’ disease. Based on such results, three hydrogenated and two hydrolyzed derivatives (10-14) were prepared and evaluated as well. The dihydropyridone amides (1-3) displayed higher anti-trypanosomal activity. The (Z)-piplartine (1) showed higher activity with a 50% inhibition concentration (IC50) value of 10.5 μM, almost four times more potent than the pos. control, benznidazole (IC50 = 42.7 μM), and should be further evaluated as a suitable hit for the design of new antiprotozoal agents. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics