2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Electric Literature of C13H11BrN2O
CuI/L-proline-catalyzed intramolecular aryl amination: an efficient route for the synthesis of 1,4-benzodiazepinones was written by Majumdar, K. C.;Ganai, Sintu. And the article was included in Synlett in 2011.Electric Literature of C13H11BrN2O The following contents are mentioned in the article:
An effective protocol for the synthesis of potentially bioactive benzo[e]chromeno[6,5-b][1,4]diazepine-3,8(7H,13H)-dione and dibenzo[b,e][1,4]diazepin-11(10H)-one derivatives in good to excellent yields has been achieved by CuI/L-Proline catalyzed coupling reaction as the key step. The methodol. offers clean reaction conditions and easy isolation of the products in 61-92% yields. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5Electric Literature of C13H11BrN2O).
2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Electric Literature of C13H11BrN2O
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics