Chemical constituents and antibacterial activity from the stems and leaves of Piper wallichii was written by Nongmai, Chalini;Kanokmedhakul, Kwanjai;Promgool, Trinop;Paluka, Jakkapat;Suwanphakdee, Chalermpol;Kanokmedhakul, Somdej. And the article was included in Journal of Asian Natural Products Research in 2022.Application In Synthesis of (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:
A phytochem. investigation of the stems and leaves of Piper wallichii led to the isolation of two new compounds, an aryl alkanone, piwalkanone () and a dioxoaporphine alkaloid, piwallidione (), together with nine known compounds, a dioxoaporphine alkaloid, cepharadione A (); two aristolactams, piperolactam A () and stigmalactam (); a piperidine, piperine (); four isobutylamides, piperlonguminine (), pellitorine (), N-isobutyl-2E,4E-octadecadienamide (), and guineensine (); and a tyramine, N-trans-feruloyltyramine (). Their structures were elucidated on the basis of spectroscopic evidence (IR, 1H NMR, 13C NMR and 2 D NMR) and MS. Compounds and showed inhibitory activities against pathogenic bacteria, Bacillus cereus, Bacillus subtilis and Staphylococcus aureus. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Application In Synthesis of (2E,4E)-N-Isobutyldeca-2,4-dienamide).
(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Application In Synthesis of (2E,4E)-N-Isobutyldeca-2,4-dienamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics