Mitsudera, Hiroyuki published the artcileStudies on nereistoxin and its related compounds. II. Synthesis and insecticidal activity of 5-dimethylamino-1,3-dithianes, Safety of 2-Cyano-N-ethylacetamide, the publication is Nippon Noyaku Gakkaishi (1991), 16(3), 397-404, database is CAplus.
Twenty-five 2-cyano-5-(dimethylamino)-2-(substituted phenyl)-1,3-dithianes I (R = H, 4-F, 4-Me, 3-CF3, 2-MeO, 3,4-Cl2, etc.) and 22 2-cyano-5-(dimethylamino)-2-(substituted carbamoyl)-1,3-dithianes II (R1 = NH2, NHMe, NHEt, NMe2, etc.) were synthesized and tested for their insecticidal and miticidal activities toward larvae of Chilo suppressalis, Laodelphax striatellus, Henosepilachna vigintioctapinctata, and Spodoptera litura and Tetranychus urticae adults. All compounds had high activities toward insects and mites tested, I (R = 4-Br) and II (R1 = NHC9H19) having highest activities. Conversion of I and II into 4-(dimethylamino)-1,2-dithiolane and/or its 1-oxide in the living body and the effect of electron-withdrawing groups at the 2-position on the penetration of I and II into the body were suggested.
Nippon Noyaku Gakkaishi published new progress about 15029-36-4. 15029-36-4 belongs to amides-buliding-blocks, auxiliary class Nitrile,Amine,Aliphatic hydrocarbon chain,Amide, name is 2-Cyano-N-ethylacetamide, and the molecular formula is C5H8N2O, Safety of 2-Cyano-N-ethylacetamide.
Referemce:
https://en.wikipedia.org/wiki/Amide,
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