Month: November 2022

Evjen, Sigvart published the artcileDegradative Behavior and Toxicity of Alkylated Imidazoles, Formula: C2H5NO, the main research area is degradation toxicity corrosivity alkylated imidazole solvent carbon dioxide.

The thermal and oxidative degradation behavior and the corrosiveness of imidazole (Im), 2-methylimidazole (2MIm), 2-ethyl-4-methylimidazole (2E4MIm), 2,4,5-trimethylimidazole (2,4,5MIm), and 1,2,4,5-tetramethylimidazole (1,2,4,5MIm) were investigated in a CO2 rich environment. The imidazoles demonstrated high thermal stability in all solutions; however, Im and 2MIm were corrosive. Polyalkylated imidazoles were less stable toward oxidation compared to Im. Rat cell (PC-12) toxicol. screening of Im and 45 alkylated imidazoles showed reduced toxicity for polyalkylated imidazoles compared to Im. Cell viability correlated neg. with cLogP predictions when cLogP > 3. The high rate of oxidative degradation and formation of potentially carcinogenic degradation products will prevent the use of polyalkylated imidazoles in industrial processes directed toward CO2.

Industrial & Engineering Chemistry Research published new progress about Corrosives. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Formula: C2H5NO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Silva, Murilo O. published the artcileEffect of single and double methylation on the position of the π* shape resonance of formamide and acetamide, Quality Control of 123-39-7, the main research area is formamide acetamide methylation ground state.

In this work we report calculated integral and differential cross sections for elastic electron collision with formamide, acetamide and their resp. methylated derivatives, for impact energies up to 6 eV. Our calculations were performed with the Schwinger multichannel method with pseudopotentials, in the static-exchange and static-exchange plus polarization approximations The aim of this work is to investigate the methylation effect on the π* shape resonance, which is present in the A’spm symmetry of all studied systems. Our results were compared with existent data from the literature and showed good agreement. Stabilization or destabilization of the π* resonance due to methylation occur, but there is no clear tendency on stabilization or destabilization among the methylated derivatives Changes in the widths of the resonance due to the Me group were also observed

Chemical Physics published new progress about Conformers. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Quality Control of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yang, Hongxing published the artcilePigmentiphaga sp. strain D-2 uses a novel amidase to initiate the catabolism of the neonicotinoid insecticide acetamiprid, Application In Synthesis of 123-39-7, the main research area is Pigmentiphaga amidase neonicotinoid acetamiprid catabolism; AceAB; IM 1-4; Pigmentiphaga sp. strain D-2; acetamiprid; amidase; initial hydrolysis.

Acetamiprid, a chloronicotinyl neonicotinoid insecticide, is among the most commonly used insecticides worldwide, and its environmental fate has caused considerable concern. The compound 1-(6-chloropyridin-3-yl)-N-methylmethanamine (IM 1-4) has been reported to be the main intermediate during acetamiprid catabolism in microorganisms, honeybees, and spinach. However, the mol. mechanism underlying the hydrolysis of acetamiprid to IM 1-4 has not yet been elucidated. In this study, a novel amidase (AceAB) that initially hydrolyzes the C-N bond of acetamiprid to generate IM 1-4 was purified and characterized from the acetamiprid-degrading strain Pigmentiphaga sp. strain D-2. Based on peptide profiling of the purified AceAB and the draft genome sequence of strain D-2, aceA (372 bp) and aceB (2,295 bp), encoding the α and β subunits of AceAB, resp., were cloned and found to be necessary for acetamiprid hydrolysis in strain D-2. The characteristics of AceAB were also systematically investigated. Though AceA and AceB showed 35% to 56% identity to the α and β subunits of the N,N-dimethylformamidase from Paracoccus aminophilus, AceAB was specific for the hydrolysis of acetamiprid and showed no activities to N,N-dimethylformamide or its structural analogs.

Applied and Environmental Microbiology published new progress about Catabolism. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application In Synthesis of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Zhao, Jian-Qiang published the artcileLead chlorine cluster assembled one-dimensional halide with highly efficient broadband white-light emission, Name: N-Methylformamide, the main research area is lead chlorine cluster halide broadband white light emission.

One new type of hybrid lead halide of [DTHPE]2Pb3Cl10 has been synthesized and characterized containing a one-dimensional (1D) wavelike [Pb3Cl10]4- chain based on a corner-shared [Pb3Cl11] cluster. Remarkably, this cluster-based 1D chain displays intrinsic broadband white light emission with a high quantum efficiency of 19.45% exceeding those of previously reported typical two-dimensional perovskites.

Chemical Communications (Cambridge, United Kingdom) published new progress about Bond angle. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Name: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Zuo, Chenpeng published the artcileA theoretical study of hydrogen-bonded molecular clusters of sulfuric acid and organic acids with amides, Quality Control of 123-39-7, the main research area is hydrogen bond mol cluster sulfuric acid organic amide; Amides; Hydrogen bond; Nucleation; Organic acids; Sulfuric acid.

Amides, a series of significant atm. nitrogen-containing volatile organic compounds (VOCs), can participate in new particle formation (NPF) through interacting with sulfuric acid (SA) and organic acids. In this study, we investigated the mol. interactions of formamide (FA), acetamide (AA), N-methylformamide (MF), propanamide (PA), N-methylacetamide (MA), and N, N-dimethylformamide (DMF) with SA, acetic acid (HAC), propanoic acid (PAC), oxalic acid (OA), and malonic acid (MOA). Global min. of clusters were obtained through the association of the artificial bee colony (ABC) algorithm and d. functional theory (DFT) calculations The conformational anal., thermochem. anal., frequency anal., and topol. anal. were conducted to determine the interactions of hydrogen-bonded mol. clusters. The heterodimers formed a hepta or octa membered ring through four different types of hydrogen bonds, and the strength of the bonds are ranked in the following order: SO-HO > CO-HO > N-HO > C-HO. We also evaluated the stability of the clusters and found that the stabilization effect of amides with SA is weaker than that of amines with SA but stronger than that of ammonia (NH3) with SA in the dimer formation of nucleation process. Addnl., the nucleation capacity of SA with amides is greater than that of organic acids with amides.

Journal of Environmental Sciences (Beijing, China) published new progress about Bond angle. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Quality Control of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Zhou, Jing published the artcileFructus Gardeniae-induced gastrointestinal injury was associated with the inflammatory response mediated by the disturbance of vitamin B6, phenylalanine, arachidonic acid, taurine and hypotaurine metabolism, Computed Properties of 123-39-7, the main research area is vitamin B phenylalanine arachidonic acid taurine hypotaurine metabolism; Fructus Gardeniae; Gastrointestinal injury; HPLC-TOF-MS/MS; Metabolomics.

Fructus Gardenia (FG) is a widely used bitter and cold herb for clearing heat and detoxicating. Currently, toxicity of FG and its relative formula has been reported in many clin. and animal studies. However, no systematic research has been carried out on FG-related gastrointestinal (GI) injury which has been emphasized in China since the Ming Dynasty. The purpose of this article is to investigate whether FG could damage GI and explore the mechanisms involved. FG was given to male mice by 7-day intragastric administration at average doses of 0.90 g (L group), 1.50 g (M group), and 3.00 g (H group) crude drug/kg FG. Comprehensive understanding of changes in weight, diarrhea degree, stool routine, histomorphol. and inflammatory factors of stomach, small intestine, and colon for evaluating the effect of different doses of FG on GI injury. Moreover, metabolomics-based mechanisms exploration of FG on GI injury was carried out via HPLC-Q-TOF/MS anal. on mice urine. High dose FG caused GI injury with serious diarrhea, decreased weight, abnormal stool routine, sever alteration in histomorphol. of small intestine and colon (mild change in stomach), and significant change in inflammatory factors. The results of metabolomics suggested that 55 endogenous metabolites dispersed in 21 significantly altered metabolic pathways in 3.00 g/kg crude FG treated mice. The hub metabolites of GI injury were mainly related with vitamin B6 metabolism, phenylalanine metabolism, arachidonic acid metabolism, and taurine and hypotaurine metabolism via correlated network anal. FG affected the normal functions of GI via the regulating a variety of metabolic pathways to an abnormal state, and our results provided a research paradigm for the GI-injury of the relative bitter and cold traditional Chinese medicines.

Journal of Ethnopharmacology published new progress about Biomarkers. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Computed Properties of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Li, Rui published the artcileSeparation of azeotropic mixture (2, 2, 3, 3-Tetrafluoro-1-propanol + water) by extractive distillation: Entrainers selection and vapour-liquid equilibrium measurements, Computed Properties of 123-39-7, the main research area is tetrafluoropranol water azeotropic mixture extractive distillation vapor liquid equilibrium.

For separating the azeotrope of 2, 2, 3, 3-tetrafluoro-1-propanol (TFP) and water by extractive distillation, N-Me pyrrolidone (NMP), N-Me formamide (NMF) and N, N-dimethyl formamide (DMF) were selected as entrainers using the COSMO-SAC model based on solvent capacity. And the charge d. surface of entrainers and each component in the azeotrope system were calculated The vapor-liquid equilibrium (VLE) data for the mixtures (TFP + NMP), (TFP + NMF) and (TFP + DMF) were measured by a modified Rose-type recirculating still at the pressure 101.3 kPa. The thermodn. consistency for the VLE data was validated using the Herington and van Ness methods. The VLE data were correlated with NRTL, Wilson and UNIQUAC models, and the interaction parameters of thermodn. models were fitted. Meanwhile, the effect of the entrainers on the VLE for TFP and water was explored. Compared with NMF and DMF, NMP was adopted as the suitable entrainer for separation of the azeotropic mixture TFP and water by extractive distillation

Journal of Chemical Thermodynamics published new progress about Azeotropes. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Computed Properties of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Hu, Yang-mei-qing published the artcileThe preparation of polyclonal antibody against chlordimeform and establishment of detection by indirect competitive ELISA, Product Details of C2H5NO, the main research area is polyclonal antibody chlordimeform indirect competitive ELISA; Chlordimeform; IC-ELISA; artificial antigen; polyclonal antibody.

Chlordimeform is a chem. pesticide that is highly carcinogenic and toxic. The purpose of this study was to establish an ELISA (ELISA) method for the detection of chlordimeform in aquaculture and fish farming. Chlordimeform was coupled with bovine serum albumin (BSA) and ovalbumin (OVA) as carrier proteins. A chlordimeform-BSA conjugate was used as an immunogen, and chlordimeform-OVA was used as a coating antigen. Chlordimeform-BSA was used to immunize rabbits, and a polyclonal antibody was prepared An indirect competitive ELISA (IC-ELISA) was established to detect chlordimeform. The working range of the established IC-ELISA method for chlordimeform detection was 1-20 ng/mL. The IC50 was 3.126 ng/mL, and the lower limit of detection (LOD) of chlordimeform was 0.637 ng/mL. The recovery of chlordimeform from spiked water samples ranged from 81% to 107%. An anti-chlordimeform polyclonal antibody was successfully developed, and a novel IC-ELISA was established to detect chlordimeform in aquaculture.

Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes published new progress about Antiserums. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Product Details of C2H5NO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Barhoumi Meddeb, Amira published the artcileMagnetic field effects on cellulose nanocrystal ordering in a non-aqueous solvent, Application In Synthesis of 123-39-7, the main research area is cellulose nanocrystal non aqueous solvent magnetic field manipulation.

Cellulose nanocrystals (CNCs) are rod-shaped particles that can self-assemble into a chiral nematic phase at certain contents. Due to their neg. diamagnetic susceptibility and high aspect ratio, the structure of the chiral nematic phase of CNC suspensions can be manipulated using a magnetic field, which is a promising path to extending local order to a larger scale. The ability to manipulate CNCs in non-aqueous solvents is critically needed to incorporate them in a wide range of polymers. So far, magnetic field-induced manipulation of CNCs in suspension was reported for aqueous suspensions only, whereas a much-needed similar study for non-aqueous solvents has not been reported to the best of our knowledge. In this paper, we investigate the CNC ordering in n-methylformamide (NMF) under a 0.7 T magnetic field and compare it to the order achieved in H2O. The formation of a well-defined chiral nematic phase and its viscosity have a significant influence on the rate and extent of the field-induced orientation of CNCs. A clearly formed chiral nematic phase has a high potential for increased levels of field-induced ordering. And the chiral nematic phase with the lowest viscosity showed the largest increase in ordering when the magnetic field is applied before reaching equilibrium and plateauing. In contrast, the higher viscosity suspensions exhibited limited temporal changes after the initial field effect. These findings will facilitate the fabrication of globally ordered CNCs in a variety of polymers under a magnetic field, which is a necessary step to expanding the engineering applications of large-scale cellulose-based composites with anisotropic properties.

Cellulose (Dordrecht, Netherlands) published new progress about Anisotropy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application In Synthesis of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Galle, Tom published the artcileSimultaneous Ligand and Cation Exchange of Colloidal CdSe Nanoplatelets toward PbSe Nanoplatelets for Application in Photodetectors, Application In Synthesis of 123-39-7, the main research area is simultaneous ligand cation exchange colloidal cadmium selenium nanoplatelets toward.

Cation exchange emerged as a versatile tool to obtain a variety of nanocrystals not yet available via a direct synthesis. Reduced reaction times and moderate temperatures make the method compatible with anisotropic nanoplatelets (NPLs). However, the subtle thermodn. and kinetic factors governing the exchange require careful control over the reaction parameters to prevent unwanted restructuring. Here, we capitalize on the research success of CdSe NPLs by transforming them into PbSe NPLs suitable for optoelectronic applications. In a two-phase mixture of hexane/N-methylformamide, the oleate-capped CdSe NPLs simultaneously undergo a ligand exchange to NH4I and a cation exchange reaction to PbSe. Their morphol. and crystal structure are well-preserved as evidenced by electron microscopy and powder X-ray diffraction. We demonstrate the successful ligand exchange and associated electronic coupling of individual NPLs by fabricating a simple photodetector via spray-coating on a com. substrate. Its optoelectronic characterization reveals a fast light response at low operational voltages.

Journal of Physical Chemistry Letters published new progress about Anisotropy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application In Synthesis of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics