Month: November 2022

Tsutsumi, Shinichi published the artcileMeasurement of Hansen solubility parameter on pollen particle surface using capillary penetration method, Recommanded Product: N-Methylformamide, the main research area is Hansen solubility parameter pollen particle surface capillary penetration.

Pollen from species such as cedar and ragweed can neg. affect human health, and this is a problem around the world. Various attempts were made to mitigate the effects of pollen on human health. This study was focused on removing pollen from air by efficiently collecting the pollen. To achieve that requires the phys. properties of the pollen surfaces to be understood. Hansen solubility parameters (HSPs) are useful for evaluating the surfaces of particles made of materials such as ZrO2, TiO2, and SiO2. However, it is difficult to evaluate the surfaces of particles made of biomaterials (e.g., pollen and mite and flea carcasses) because of the complex surface structures of such particles. In this paper, HSPs for pollen particle surfaces were measured using the capillary permeation method, which can be used to evaluate even particles with complicated shapes. The chem. structures of the pollen surfaces were then investigated to provide data to validate the measured HSPs. The measured cedar pollen HSPs were (δd, δp, δh) = (15.8, 5.4, 11.7), and the measured cypress pollen HSPs were (δd, δp, δh) = (16.0, 4.7, 11.3). A liquid mixture designed to be compatible with the HSPs was also developed.

Materials Chemistry and Physics published new progress about Ambrosia (pollen). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Welsh, Erin N. published the artcileShort syntheses of 1-substituted dibenzothiophene derivatives, Application of (S)-2-Methylpropane-2-sulfinamide, the main research area is dibenzothiophene preparation.

A simple one-pot preparation of 1-lithiodibenzothiophene from com. materials via a cascade of two benzyne additions and conversion to several derivatives I (R = I, CHO, CN, C(O)CF3, etc.) by addition of electrophiles (N,N-dimethylformamide, benzaldehyde, 1-propanal, etc.) was demonstrated. A chiral amine containing the 1-dibenzothiophenes motif II (R1 = H, (S)-S(O)C(CH3)3; R2 = Me, Et) was also prepared This work avoids the use of precious metals or tert-butyllithium and is much shorter and more convenient than existing routes to 1-substituted dibenzothiophenes I.

Organic & Biomolecular Chemistry published new progress about Addition reaction. 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Application of (S)-2-Methylpropane-2-sulfinamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Li, Sizhe published the artcileStereospecific Synthesis of Glycoside Mimics Through Migita-Kosugi-Stille Cross-Coupling Reactions of Chemically and Configurationally Stable 1-C-Tributylstannyl Iminosugars, Name: (S)-2-Methylpropane-2-sulfinamide, the main research area is iminosugar glycoside mimic stereospecific synthesis; Migita Kosugi Stille coupling configurational stable tributylstannyl iminosugar.

A process for the de novo synthesis of imino-C-glycosides is described. The methodol. is based on the reaction of 1-C-stannylated iminosugars with various electrophiles under the conditions of Migita-Kosugi-Stille cross-couplings, which gives 1-C-substituted iminosugar derivatives in a stereoretentive process. The required iminoglycosyl stannanes are obtained by way of the highly stereoselective addition of tributylstannyllithium to (SR)- or (SS)-N-tert-butanesulfinyl glycosylamines, followed by an activation cyclization sequence. Most interestingly, the methodol. is tunable: the configuration of the tin adduct is controlled exclusively by the tert-butanesulfinyl auxiliary, thus giving access after ring formation to ‘α’-configured or ‘β’-configured iminoglycosyl stannanes. With the subsequent stereoretentive C-C bond-forming process, the methodol. allows the synthesis of pseudo anomers of imino-C-glycosyl compounds in a controlled fashion.

Advanced Synthesis & Catalysis published new progress about Addition reaction. 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Name: (S)-2-Methylpropane-2-sulfinamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ma, Jing published the artcileProton transfer reaction of the formamide and its derivatives characterized via the Kohn-Sham potential, HPLC of Formula: 123-39-7, the main research area is formamide derivative proton transfer reaction Kohn Sham potential.

Proton transfer (PT) reaction plays a critical role in chem. and biol. processes, but the bond breaking and forming during the reaction as well as the charge change are rarely concerned. In this work, Kohn-Sham potential (KSpot) quantum chem. topol. (QCT) method is used to partition a mol. into resp. basins and yield a new at. charge model. The bond critical point and Dpb gained from KSpot are applied to determine chem. bond forming and estimate the bond strength, resp. Moreover, KSpot mol. face has been defined by the KSpot that presents the reactive site of formamide during PT process. In general, KSpot method can present the charge change, visualize reactive sites and quantify the chem. bond strength in the PT process, which can be considered as the cornerstone for other chem. reactions.

Computational & Theoretical Chemistry published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, HPLC of Formula: 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Andreou, Fevronia T. published the artcileIntercalation of N-methylformamide in kaolinite: In situ monitoring by near-infrared spectroscopy and X-ray diffraction, HPLC of Formula: 123-39-7, the main research area is methylformamide kaolinite IR spectroscopy Xray diffraction.

The selective self-assembly of small mols. in the interlayer of kaolinite is a fundamentally important and technol. relevant process, typically studied ex situ by X-ray diffraction (XRD). Near-IR (NIR) spectroscopy is now introduced to provide a complementary local structural description of intercalation with improved control of exptl. conditions. New NIR- and XRD-based proxies were developed and applied to the real-time monitoring of N-methylformamide (NMF) intercalation in two reference kaolinites differing in stacking order. The commonly employed XRD-based formalism was found to overestimate reaction progress. The bonding of NMF in the interlayer was independent of reaction progress and kaolinite type. Both NIR and XRD recorded identical sigmoidal kinetics. Isothermal NIR monitoring (25-80°C) yielded time-temperature superimposable sigmoidals with an apparent activation energy of ∼60 kJ/mol, common to both samples. All NIR and XRD data series could be described as linear combinations of empty and fully intercalated kaolinite. The filling of the interlayer was too fast to be observed The sigmoidal curves were instead modeled as the log-normally distributed response of an ensemble of intercalating entities, presumably crystallites. The multiplicative standard deviation of the distribution, which determines its steepness, is a sample-specific, temperature-independent property of kaolinite.

Applied Clay Science published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, HPLC of Formula: 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Volli, Vikranth published the artcileOxidative stability, thermal hazard analysis, and decomposition kinetics of 1-methylimidazolium nitrate via DSC, TGA, and GC/MS, Safety of N-Methylformamide, the main research area is methylimidazolium nitrate oxidative stability thermal hazard analysis decomposition kinetics.

Imidazolium-based ionic liquids are green solvents used as separation and electrolyte media in liquid-liquid extraction processes and electrochem. devices. However, they are volatile and flammable once they reach their thermal decomposition temperatures In the present study, the oxidative stability, decomposition, and combustion reaction of 1-methylimidazolium nitrate [Mim][NO3] were investigated via thermogravimetric anal. (TG) and differential scanning calorimetry (DSC). TG anal. revealed a single-stage mass loss between 117.6 and 230.2 °C with oxidative onset temperatures in the range of 126.6-163.2 °C with the increase in heating rate (1.0, 2.0, 4.0, and 8.0 °C min-1). DSC results indicated the degradation as exothermic with the average enthalpy of decomposition as 1610.4 J g-1. The estimated average value of apparent activation energy using isoconversional methods such as Kissinger, FWO, and Friedman was in the range of 106.1-114.2 kJ mol-1, and the reaction function (autocatalytic model) is expressed as: f(α) = (1 – α)1.42 (0.017 + α0.62) using multivariate nonlinear regression. The GC/MS anal. revealed the formation of methane isocyanate indicating the hazardous, toxic, corrosive, and carcinogenic nature of the decomposed gases. This research was aimed to develop a predictive model for oxidative degradation behavior and to provide the necessary basis for the design of precise safety systems.

Journal of Thermal Analysis and Calorimetry published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Safety of N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Vivek, J. Padmanabhan published the artcileNegating the Interfacial Resistance between Solid and Liquid Electrolytes for Next-Generation Lithium Batteries, Formula: C2H5NO, the main research area is negate interfacial resistance solid liquid electrolyte lithium battery water; electrolyte additives; lithium metal batteries; lithium−ion transport; solid−liquid electrolyte interphases; solid−liquid hybrid electrolytes.

The combination of solid and liquid electrolytes enables the development of safe and high-energy batteries where the solid electrolyte acts as a protective barrier for a high-energy lithium metal anode, while the liquid electrolyte maintains facile electrochem. reactions with the cathode. However, the contact region between the solid and liquid electrolytes is associated with a very high resistance, which severely limits the specific energy that can be practically delivered. In this work, we demonstrate a suitable approach to virtually suppress such interfacial resistance. Using a NASICON-type solid electrolyte in a variety of liquid electrolytes (ethers, DMSO, acetonitrile, ionic liquids, etc.), we show that the addition of water as electrolyte additive decreases the interfacial resistance from >100 Ω cm2 to a negligible value (<5 Ω cm2). XPS measurements reveal that the composition of the solid-liquid electrolyte interphase is very similar in wet and dry liquid electrolytes, and thus the suppression of the associated resistance is tentatively ascribed to a plasticizer or preferential ion solvation effect of water, or to a change in the interphase morphol. or porosity caused by water. Our simple estimates show that the improvement in the solid-liquid electrolyte interphase resistance observed here could translate to an enhancement of 15-22% in the practical energy d. of a Li-S or Li-O2 battery and improvements in the roundtrip efficiency of 21-28 percentage points. ACS Applied Materials & Interfaces published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Formula: C2H5NO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Dominguez, Rodrigo published the artcileElucidation of the photodegradation mechanism of CCl3C(O)NH2, CClF2C(O)NH2 and CF3C(O)NH2 in solid state (266 nm) and solution (254 nm). Experimental and theoretical studies, Safety of 2,2-Difluoroacetamide, the main research area is trifluoroacetamide trichloroacetamide difluoroacetamide photodegradation absorption electronic transition.

In this work we present the study of the direct photolysis processes for 2,2,2-trichloroacetamide (TCA), 2-chloro-2, 2-difluoroacetamide (CDFA) and 2,2,2-trifluoroacetamide (TFA), in solid state and solution CH3OH, CH3CN and H2O were used as solvents, and the irradiation (254 nm) was carried out in oxygen enriched as well as in oxygen free (N2 bubbled) solutions The 266 nm light was reserved for the solid samples. In solution, the process was followed by UV-vis spectroscopy and the products analyzed by gas chromatog. coupled to mass spectrometry (GC-MS); while the gas phase products from the solid photodegradation processes, were followed by FTIR spectroscopy. The main electronic transitions were assigned on the bases of chem. calculations, and they do corroborate the proposed mechanisms. For both TCA and CDFA, the breakdown of the C-Cl bond is observed as the major process, with an activation energy of around 42 kcal/mol (in solution) and 27 kcal/mol (in gas phase), and a quantum yield of 0.01. TFA does not degrade under these exptl. conditions.

Journal of Photochemistry and Photobiology, A: Chemistry published new progress about Activation energy. 359-38-6 belongs to class amides-buliding-blocks, name is 2,2-Difluoroacetamide, and the molecular formula is C2H3F2NO, Safety of 2,2-Difluoroacetamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Owen, Aniekan Ekpenyong published the artcileManganese-Catalyzed Dehydrogenative Synthesis of Urea Derivatives and Polyureas, Related Products of amides-buliding-blocks, the main research area is amine methanol manganese catalyst dehydrogenative coupling reaction; formamide amine manganese catalyst dehydrogenative coupling reaction; urea preparation.

Here the synthesis of (poly)ureas using much less toxic reagents-(di)amines and methanol-via a catalytic dehydrogenative coupling process. The reaction was catalyzed by a pincer complex of an earth-abundant metal, manganese, and liberates H2 gas, valuable by itself, as the only byproduct, making the overall process highly atom-economic. A broad variety of sym. and unsym. urea derivatives and polyureas was synthesized in moderate to quant. yields using this catalytic protocol. Mechanistic insights was also been provided using experiments and DFT computation, suggesting that the reaction proceeds via an isocyanate intermediate.

ACS Catalysis published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Related Products of amides-buliding-blocks.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Li, Hu published the artcileA Facile Direct Route to N-(Un)substituted Lactams by Cycloamination of Oxocarboxylic Acids without External Hydrogen, Recommanded Product: N-Methylformamide, the main research area is lactam preparation oxocarboxylic acid formamide water cycloamination green chem; amination; cyclization; density functional calculations; lactams; reduction.

Lactams are privileged in bioactive natural products and pharmaceutical agents and widely featured in functional materials. This study presents a novel versatile approach to the direct synthesis of lactams from oxocarboxylic acids without catalyst or external hydrogen. The method involves the in situ release of formic acid from formamides induced by water to facilitate efficient cycloamination. Water also suppresses the formation of byproducts. This unconventional pathway is elucidated by a combination of model experiments and d. functional theory calculations, whereby cyclic imines (5-methyl-3,4-dihydro-2-pyrrolone and its tautomeric structures) are found to be favorable intermediates toward lactam formation, in contrast to the conventional approach encompassing cascade reductive amination and cyclization. This sustainable and simple protocol is broadly applicable for the efficient production of various N-unsubstituted and N-substituted lactams.

ChemSusChem published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics