Month: November 2022

On October 31, 2022, Gao, Hui; Zhao, Fuqiang; Li, Ruijing; Jin, Shuaichen; Zhang, Haibo; Zhang, Keyu; Li, Shisheng; Shu, Qin; Na, Guangshui published an article.COA of Formula: C8H10N2O3S The title of the article was Occurrence and distribution of antibiotics and antibiotic resistance genes in water of Liaohe River Basin, China. And the article contained the following:

Surface water environment is an important repository of antibiotics and antibiotic resistance genes (ARGs). It is of great significance to study the occurrence and distribution of antibiotics and ARGs in surface water environment. In this study, the Liaohe River Basin, China was taken as the study area, and the concentrations of antibiotics and ARGs in water were investigated by HPLC-MS/MS and HT-qPCR. The results showed that a total of 53 antibiotics of 6 types were detected in water, and the pollution level was at ND∼331.64 ng/L, where PCG was the highest. Totally 164 ARGs and 10 mobile genetic elements (MGEs) were detected in the water, and the absolute abundances were at 2.18 × 104∼3.95 × 107 copies/L and 1.82 × 105-3.78 × 107 copies/L, resp. The multidrug and aminoglycoside were the dominant ARG types. Amoxicillin, erythromycin, anhydroerythromycin and ofloxacin posed certain ecol. risks for sensitive aquatic organisms. In spatial distribution, the pollution of antibiotics and ARGs in the Daliao River system was higher than that in the Liaohe River system. There was a significant pos. correlation between total concentrations of antibiotics and total relative abundance of ARGs (r = 0.66, p < 0.05). The co-occurrence of multiple antibiotics promoted the pollution and spread of ARGs. In addition, the total relative abundance of MGEs and ARGs showed a significant pos. correlation (r = 0.946, p < 0.01), and MGEs played an important role in the occurrence and evolution of ARGs in water. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).COA of Formula: C8H10N2O3S

The Article related to antibiotic resistance gene occurrence distribution water hplc ms, Water: Analysis and other aspects.COA of Formula: C8H10N2O3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 18, 2020, Cuthbertson, Amy A.; Liberatore, Hannah K.; Kimura, Susana Y.; Allen, Joshua M.; Bensussan, Alena V.; Richardson, Susan D. published an article.Recommanded Product: 2-Chloroacetamide The title of the article was Trace Analysis of 61 Emerging Br-, Cl-, and I-DBPs: New Methods to Achieve Part-Per-Trillion Quantification in Drinking Water. And the article contained the following:

Disinfection byproducts (DBPs) are a ubiquitous source of chem. exposure in drinking H2O and were associated with serious health impacts in human epidemiol. studies. While toxicol. studies have pinpointed DBPs with the greatest toxic potency, anal. methods were lacking for quantifying complete classes of most toxic DBPs at sufficiently low quantification limits (ng/L). This new method reports the parts-per-trillion quantification for 61 toxicol. significant DBPs from 7 different chem. classes, including unregulated iodinated haloacetic acids (HAAs) and trihalomethanes (THMs), haloacetaldehydes, haloketones, haloacetonitriles, halonitromethanes, and haloacetamides, in addition to regulated HAAs and THMs. The final optimized method uses salt-assisted liquid-liquid extraction in a single extraction method for a wide range of DBPs, producing the lowest method detection limits to-date for many compounds, including highly toxic iodinated, brominated, and N-containing DBPs. Extracts were divided for the anal. of the HAAs (including iodinated HAAs) by diazomethane derivatization and anal. using a GC-triple quadrupole mass spectrometer with multiple reaction monitoring, resulting in higher signal-to-noise ratios, greater selectivity, and improved detection of these compounds The remaining DBPs were analyzed using a GC-single quadrupole mass spectrometer with selected ion monitoring, using a multimode inlet allowed for lower injection temperatures to allow the anal. of thermally labile DBPs. Finally, the use of a specialty-phase GC column (Restek Rtx-200) significantly improved peak shapes, which improved separations and lowered detection limits. Method detection limits for most DBPs were 15-100 ng/L, and relative standard deviations in tap H2O samples were mostly between 0.2 and 30%. DBP concentrations in real samples ranged from 40 to 17,760 ng/L for this study. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Recommanded Product: 2-Chloroacetamide

The Article related to trace halo disinfection byproduct part per trillion drinking water, Water: Analysis and other aspects.Recommanded Product: 2-Chloroacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 15, 2021, Zhang, Ruiling; Kang, Yaru; Zhang, Ruijie; Han, Minwei; Zeng, Weibin; Wang, Yinghui; Yu, Kefu; Yang, Ying published an article.Related Products of 144-80-9 The title of the article was Occurrence, source, and the fate of antibiotics in mariculture ponds near the Maowei Sea, South China: Storm caused the increase of antibiotics usage. And the article contained the following:

Antibiotic residues in mariculture environments have been detected globally, while little information is available about their dynamic levels, source, behavior, and fate during the whole culture process. In this study, the dynamic occurrence, bioaccumulation, source, fate, and human dietary risk of 19 antibiotics were investigated in different breeding stages of mariculture ponds near the Maowei Sea, South China. Fourteen antibiotics, including three sulfonamides (SAs), five fluoroquinolones (FQs), three macrolides (MLs), and two chloramphenicols (CAPs), were detected in the mariculture ponds, with FQs being the most abundant antibiotics. Significant variations of antibiotic concentration occurred during the whole culture process. Severe weather, especially typhoons and rainstorms, resulted in the average highest levels of ∑19antibiotics (mean: 567 ng L-1) in mariculture ponds. The source apportionment estimated for the mariculture ponds showed that direct application was the primary source of antibiotics (91.2%). The antibiotics in mariculture ponds were mainly discharged through aquaculture wastewater (65.8%) and settling particles (33.8%). The estimated annual input of antibiotics into the Maowei Sea was 2.24 times higher through the two main rivers (48.0 kg a-1) than through the mariculture wastewater (24.1 kg a-1). The apparent bioaccumulation factors (ABAFs) confirmed that young and adult tilapia accumulated more sulfamethoxazole (SMX) and norfloxacin (NOX), resp. The result from the estimated daily intakes suggested that the antibiotics in the seafood could not pose a risk to human health by dietary exposure assessment. Big variation of antibiotic concentration occurred during the whole culture process in the mariculture farms, and the storm increased antibiotic application. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Related Products of 144-80-9

The Article related to antibiotics mariculture pond seawater, antibiotics, dietary risk, environmental fate, mariculture ponds, source, Water: Analysis and other aspects.Related Products of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 30, 2022, Liu, Jing; Deng, Wen-Jing; Ying, Guang-Guo; Tsang, Eric P. K.; Hong, Hua-Chang published an article.HPLC of Formula: 144-80-9 The title of the article was Occurrence and distribution of antibiotics in surface water. And the article contained the following:

The concentrations, distribution, and ecol. risks of 24 typical antibiotics in Hong Kong rivers and seawater were investigated using high-performance liquid chromatog. coupled with electrospray ionization tandem mass spectrometry (UHPLC-EI-MS/MS). The results showed that the select antibiotics were widely distributed in the study area. Among the target antibiotics, the detection rate of tetracyclines (TCs) was 100%, which indicated the widespread use of TCs in Hong Kong. The detection rates of sulfonamides (SAs) (57.1-100%), fluoroquinolones (FQs) (78.6-100%), roxithromycin (RTM) (50%) and novobiocin (NOV) (50%) were all above 50%. Compared with river water (7.9-114.26 ng/L, medium: 27.7 ng/L), concentrations of the most antibiotics in seawater (9.5-32.0 ng/L, medium: 13.3 ng/L) were lower; seawater concentrations were similar to those reported from other coastal cities, such as Guangzhou and Zhuhai in China, which implied that the source of marine antibiotic pollution may be the nearby rivers, and the vastness of the ocean causes environmental dilution of antibiotics. According to the ratio of the measured environmental concentration (MEC) to the predicted no-effect concentration (PNEC), ofloxacin (OFX) (average risk quotient: 1.94E-01) and ciprofloxacin (CFX) (average risk quotient: 3.53E-01) posed medium to high ecol. risk in most places, whereas other antibiotics posed lower risk. In Yuen Long, where there were many livestock farms nearby, the detected concentration of antibiotics was higher, indicating that livestock wastewater may be the major reason for the increase in antibiotic levels in this area. In general, the detected concentration of antibiotics in Hong Kong was lower than that in the United States, Japan, the United Kingdom, and coastal areas of China, but the long-term existence of low concentrations of antibiotics also poses great risks. According to the risk assessment, Hong Kong should pay more attention to the use of FQs (e.g., OFX and CFX) in the future. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).HPLC of Formula: 144-80-9

The Article related to occurrence distribution antibiotics surface water, antibiotics, aquatic environment, ecological risk, uhplc-ms/ms, Water: Analysis and other aspects.HPLC of Formula: 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 15, 2021, Lv, Yin-Zhi; Luo, Xiao-Jun; Zhao, Jian-Liang; Wang, Shan-Quan; Mai, Bi-Xian published an article.Safety of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Occurrence and distribution of antibiotics in sediments from black-odor ditches in urban areas from China. And the article contained the following:

Antibiotic levels in black-odor water could reflect the usage amount of antibiotics in population. On the other hand, these antibiotics are the source of antibiotics in the environmental water. Currently, researches on antibiotics in black-odor sediments are still lacking. In this study, 174 black and odor sediment samples from 74 cities in 28 provinces in China were collected for anal. Among 44 targeted antibiotics, 13 antibiotics were detected in more than 30% of sediment samples. Fluoroquinolones and tetracyclines were the predominant antibiotics in these field samples, with average concentrations of up to 2074 and 1902 ng/g dry weight (dw), resp., followed by macrolides (87.9 ng/g dw), lincosamides (8.06 ng/g dw) and sulfonamides (8.38 ng/g dw). High antibiotic contamination levels were almost always detected in black-odor sludges from economically less developed small cities; however, the difference in antibiotic concentrations between well-developed and small cities in China was not statistically significant. In addition, among the seven regions within China, no significant difference in concentrations was observed for the most antibiotics. Variances in antibiotic composition patterns in the 28 provinces of China may be due to differences in bacterial resistance, prescription habits, efficacy, and sediment carbon concentrations among various regions. There were significant pos. correlations among some antibiotics in the same or different classes. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Safety of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to ciprofloxacin enrofloxacin black odor ditch sediment china, antibiotics, black-odor sediments, distribution pattern, occurrence, Water: Analysis and other aspects.Safety of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 31, 2021, Da Le, Nhu; Hoang, Anh Quoc; Hoang, Thi Thu Ha; Nguyen, Thi Anh Huong; Duong, Thi Thuy; Pham, Thi Mai Huong; Nguyen, Tien Dat; Hoang, Van Chung; Phung, Thi Xuan Binh; Le, Huu Tuyen; Tran, Cao Son; Dang, Thu Hien; Vu, Ngoc Tu; Nguyen, Trong Nghia; Le, Thi Phuong Quynh published an article.Formula: C8H10N2O3S The title of the article was Antibiotic and antiparasitic residues in surface water of urban rivers in the Red River Delta (Hanoi, Vietnam): concentrations, profiles, source estimation, and risk assessment. And the article contained the following:

Antibiotic residues and antimicrobial resistance in surface water are issues of global concern, especially in developing countries. In this study, the occurrence of seven antibiotics and one antiparasitic agent was determined in surface water samples collected from four rivers running through Hanoi urban area in the Red River Delta, northern Vietnam. The pharmaceuticals in water samples were analyzed by solid-phase extraction combined with liquid chromatog.-tandem mass spectrometry method. The concentrations of pharmaceuticals in our samples ranged from 3050 to 16,700 (median 7800) ng/L, which were generally higher than levels found in river water from many other locations in the world. Amoxicillin, oxfendazole, and lincomycin were the most dominant and frequently detected compounds (detection rate 100%), which together accounted for 76 ± 14% of total concentrations Antibiotic concentrations in the water samples were not significantly different between the investigated rivers. Meanwhile, levels of pharmaceuticals in the samples collected in Feb. 2020 were higher than those found in the remaining samples, largely due to the sharp decrease in sulfamethoxazole and azithromycin concentrations of the samples collected in March and Apr. Considerable ecol. risks of antibiotics in surface water were estimated for some compounds such as amoxicillin, ciprofloxacin, and ofloxacin. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Formula: C8H10N2O3S

The Article related to antibiotic antiparasitic residue surface water urban river, antibiotics, hanoi, risk assessment, surface water, urban pollution, Water: Analysis and other aspects.Formula: C8H10N2O3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 28, 2021, Zhu, Feng; Wang, Siqi; Liu, Yujie; Wu, Minghong; Wang, Hongyong; Xu, Gang published an article.Recommanded Product: N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Antibiotics in the surface water of Shanghai, China: screening, distribution, and indicator selecting. And the article contained the following:

The widespread existence of antibiotics has caused inevitable influence on ecol. and humans. In this study, we screened the most commonly used antibiotics, and 64 antibiotics were detected in Shanghai, an international metropolis. Most of the target substances were detected in all 46 water samples including main rivers and districts in Shanghai, with concentrations ranging from 0.02 to 502.43 ng L-1. In particular, sulfadiazine (502.43 ng L-1) had the highest maximum concentration Besides, risk quotients based on fish suggested that sulfonamides had a medium risk (0.12) in Shanghai. Correlation studies had shown that most compounds with frequencies exceeding 60% were significantly pos. correlated with the total concentration Based on further anal., sulfadiazine, sulfamerazine, and sulfapyridine were screened as indicators to reflect the pollution status of antibiotics in Shanghai for a long time. The screening conditions for these indicators include detection rate (> 60%), maximum concentration (> 100 ng L-1), RQ (> 0.01), and correlation (> 0). In addition, population d. may be the main factor for antibiotic pollution through regional comparison. In a word, this work can systematically reflect the overall situation of Shanghai antibiotics and provide support for global data comparison in the future. Meanwhile, we provided the potential indicators that can be applied in the long term and economical monitoring of antibiotics. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Recommanded Product: N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to antibiotics surface water screening distribution sewage treatment plant, antibiotics, distribution, rqs, screening, typical indicators, Water: Analysis and other aspects.Recommanded Product: N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 1, 2021, Dong, Jianwei; Xie, Hui; Feng, Ranran; Lai, Xijun; Duan, Hongtao; Xu, Ligang; Xia, Xinghui published an article.Product Details of 144-80-9 The title of the article was Transport and fate of antibiotics in a typical aqua-agricultural catchment explained by rainfall events: Implications for catchment management. And the article contained the following:

Antibiotics receive many concerns since their neg. environmental impacts are being revealed, especially in aqua-agricultural areas. Rainfall events are responsible for transferring excess contaminants to receiving waters. However, the understanding of antibiotics transport and fate responding to rainfall events was constrained by limited event-based data and lacking integrated consideration of dissolved and particulate forms. We developed an intensive monitoring strategy to capture responses of fourteen antibiotics to different types of rainfall events and inter-event low flow periods. Pollutant-rich suspended particles, as high as 1471 ng/g, were found in low flow periods while the very heavy rainfall events and consecutive rainfall events stimulated the release of antibiotics from eroded soil particles to river water. Therefore, these rainfall events drove radical increase of dissolved antibiotic concentration up to 592 ng/L and total flux up to 25.0 g/d. Sulfonamides were particularly sensitive to rainfall events because of their residues in manure-applied agricultural lands. Transport dynamics of most antibiotics were accretion whereas only clarithromycin exhibited a dilution pattern by concentration-discharge relationships. Aquaculture ponds were inferred to significantly contribute tetracycline, oxytetracycline, and clarithromycin. Conventional contaminants were compared to discriminate potential sources of antibiotics and imply effective catchment management. The results provided novel insights into event-based drivers and dynamics of antibiotics and could lead to appropriate management strategy. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Product Details of 144-80-9

The Article related to antibiotics aqua agricultural catchment rainfall events, agriculture, diffuse pollution, emerging contaminants, nutrients, suspended particles, Water: Analysis and other aspects.Product Details of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 31, 2021, Ye, Chunmeng; Shi, Jiaqi; Zhang, Xuesheng; Qin, Li; Jiang, Zhongguan; Wang, Jinhua; Li, Yucheng; Liu, Bingxiang published an article.SDS of cas: 144-80-9 The title of the article was Occurrence and bioaccumulation of sulfonamide antibiotics in different fish species from Hangbu-Fengle River, Southeast China. And the article contained the following:

As a class of synthetic sulfur drugs, sulfonamides (SAs) have been used to treat diseases and promote organism growth. Different concentrations of SAs have been detected in the water environment, which has threatened the ecol. environment. In this study, the contamination of 9 SAs in water, sediments, and 8 fish species from the Hangbu-Fengle River, China, were analyzed using UPLC-MS/MS. The total SA concentrations in surface water, sediments, and fish were ND-5.064 ng/L, ND-5.052 ng/g dry weight (d.w.), and ND-1.42 ng/g wet weight (w.w.), resp. The major compounds were sulfadiazine (SDZ), sulfamerazine (SMZ), and sulfamethoxazole (SMX) in water and fish. The SA levels of in fish from different habitat preferences revealed a spatial difference, with the order of demersal species > pelagic species. Moreover, the SA concentrations were affected by trophic guilds, indicating their decrease in the order of piscivorous fish > omnivorous fish > planktivorous fish > herbivorous fish. The obtained bioaccumulation factors showed that SMZ and SMX have strong bioenrichments in Ophiocephalus argus Cantor and Pelteobagrus fulvidraco. The risk assessment indicated that SAs did not pose significant health threats to the organisms. This research is the first report of SA contamination in the Hangbu-Fenle River, which can provide an important scientific basis for their pollution prevention and ecol. risk assessment in the aquatic environment. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).SDS of cas: 144-80-9

The Article related to occurrence bioaccumulation sulfonamide antibiotic fish species southeast china, bioaccumulation, hangbu-fengle river, risk assessment, sulfonamides, Water: Analysis and other aspects.SDS of cas: 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 15, 2022, Dong, Jianwei; Shang, Meiqi; Feng, Ranran; Song, Xin; Yan, Dandan; Xie, Hui published an article.Category: amides-buliding-blocks The title of the article was Export and risk from antibiotic remobilization from surrounding water to lake in the extreme 2020 Yangtze River basin flooding. And the article contained the following:

Global climate change increased the frequency of extreme rainfall events, leading to higher flood risk. In addition to the personal and property losses, another important consequence of a flood disaster was release and exposure risks from emerging contaminants, which was usually overlooked. The remobilization and fate of the antibiotics induced by floods remain unclear. We captured antibiotic concentrations around the Chaohu Lake after an unprecedented flood with a range of 5.0-317 ng/L. Higher concentrations in polder waters than their receiving rivers were attributed to the antibiotic release from soil particles and the sharp increase of water: soil ratio by flood storage. Source apportionment anal. of antibiotics implied that diffuse pollution by manure application and aquaculture activity was the predominant sources. Commonalities of spatial variations of antibiotics in polders were related to the condition of waterlogging and pollution source. The total antibiotic storage for all submerged polders was estimated at 27.9 kg. The concentrations and risks from pumping floodwater detained by polders into the lake were much higher than that from discharging flood directly into the lake. The retention-reaction-remobilization process would pose unexpectedly high risks for the lake. This study provided a new sight for constructing ecol. wetland flood storage areas. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Category: amides-buliding-blocks

The Article related to antibiotic remobilization exposure risk lake water, chaohu lake, cluster analysis, environmental risk, principal component analysis, source apportionment, Water: Analysis and other aspects.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics