Month: November 2022

Nigam, Vinita; Vanisha, Nambiar published an article in 2018, the title of the article was Evaluation of antioxidant profile of wild and cultivated varieties of Aegle marmelos (L) correa leaves used as anti-diabetic agent.Recommanded Product: 456-12-2 And the article contains the following content:

Aim: The objective of the present study was to evaluate the total antioxidant activity of the wild variety of AM leaves from forest of Gir Somnath, Gujarat, India and cultivated variety from Central Horticultural Experiment Station, Vejalpur, Panchmahals, Gujarat to assess the role of this plant in ethanomedicine in India. Methods: The methanolic extracts of the leaves were screened for total antioxidant capacity through Ferric Reducing Antioxidant Potential (FRAP) and 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay; Total Phenol content (TPC) through spectrophotometric technique based on Folin Ciocalteau assay and for qual. estimation of phenols, High performance Liquid Chromatog. (HPLC) was used. Results: TPC of wild and cultivated variety was 7.6% and 6.5% resp. FRAP values and IC50 value (DPPH) for wild and cultivated variety were found to be 14.65渭mol/l and 11.80渭mol/l; 437渭g/mL and 620渭g/mL resp. Wild variety was found to be superior to the cultivated one. Conclusion: This study proved that the leaves of AM leaves have high antioxidant component. AM could be used as a potential preventive intervention for free radical mediated diseases such as diabetes and as neutraceutical in medicinal formulation. Further intervention trials are needed to prove the therapeutic potential of these leaves. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Recommanded Product: 456-12-2

The Article related to antioxidant aegle correa leaves antidiabetic sugar ethanomedicine neutraceutical gujarat, Pharmaceuticals: Formulation and Compounding and other aspects.Recommanded Product: 456-12-2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Lukowska-Chojnacka, Edyta; Plenkiewicz, Jan published an article in 2011, the title of the article was Simple synthesis of 尾-acetoxy thiocyanates from oxiranes.Quality Control of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione And the article contains the following content:

A convenient and simple method for the preparation of previously unknown 尾-acetoxy thiocyanates by regioselective ring opening of the corresponding oxiranes with thiocyanate anion followed by acetylation is described. The shorter reaction times, better yields of the products, and easy workup are the advantages of this methodol. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Quality Control of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

The Article related to oxirane ammonium thiocyanate regioselective ring opening, acetoxy thiocyanate preparation, General Organic Chemistry: Synthetic Methods and other aspects.Quality Control of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On April 30, 1979, Patra, A.; Mukhopadhyay, A. K.; Ghosh, A. published an article.Recommanded Product: N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide The title of the article was Constituents of Aegle marmelos: carbon-13 NMR spectra of aurapten and marmin. And the article contained the following:

Chem. reinvestigation of A. marmelos yielded aurapten, marmin, umbelliferone, and lupeol from the bark and lupeol, sitosterol, and aegeline from the leaves. 13C NMR shifts of aurapten and marmin are discussed. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Recommanded Product: N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide

The Article related to aegle aurapten marmin nmr, aegelin aegle, umbelliferone aegle, lupeol aegle, sitosterol aegle, Plant Biochemistry: Composition and Products and other aspects.Recommanded Product: N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 29, 2022, Matsutani, Takanari; Aoyama, Kotaro; Moriuchi, Toshiyuki published an article.Electric Literature of 102-07-8 The title of the article was Oxovanadium(V)-Catalyzed Synthesis of Ureas from Disilylamines and Carbon Dioxide under Ambient Pressure. And the article contained the following:

Here, a com. available easy-to-handle oxovanadium(V) compound is demonstrated to serve as an efficient catalyst for the synthesis of ureas RNHC(O)NHR (R = n-hexyl, cyclohexyl, Ph, PhCH2CH2, etc.) from disilylamines RN(SiMe3)2 and carbon dioxide under ambient pressure. The catalytic activation of carbon dioxide proceeds without any additives, demonstrating a broad substrate scope and easy scalability to validate this catalytic activation of carbon dioxide. This catalytic system can be applied to the synthesis of unsym. ureas and chiral urea with retention of chirality. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Electric Literature of 102-07-8

The Article related to urea preparation, amine disilyl preparation carbonylation carbon dioxide oxovanadium catalyst, General Organic Chemistry: Synthetic Methods and other aspects.Electric Literature of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Das, Suman; Karmakar, Himadri; Bhattacharjee, Jayeeta; Panda, Tarun K. published an article in 2019, the title of the article was Aluminium complex as an efficient catalyst for the chemo-selective reduction of amides to amines.HPLC of Formula: 685-91-6 And the article contains the following content:

An efficient protocol for the catalytic chemo-selective reduction of tert-amides RC(O)N(R1)R2 (R = Me, Ph, 4-cyanophenyl, etc.; R1 = Me, Et, Ph, etc.; R2 = Me, Et, i-Pr; R1R2 = -(CH2)4-) with pinacolborane (HBpin) to afford the corresponding amines RCH2N(+)H(R1)R2Cl(-) in high yields using aluminum complexes I (X = S, Se) as pre-catalysts at room temp was reported. The aluminum complexes were prepared from the reaction of II (X = S, Se) and trimethylaluminum in toluene. The solid-state structure of complex I (X = Se) is established. Tertiary amides with a wide array of electron-withdrawing and electron-donating functional groups were easily converted to the desired products through the selective cleavage of the amides’ C=O bond by aluminum hydride as an active species. A kinetic study of the catalytic reaction is also reported. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).HPLC of Formula: 685-91-6

The Article related to amine tertiary preparation chemoselective, tertiary amide reduction aluminum complex catalyst, General Organic Chemistry: Synthetic Methods and other aspects.HPLC of Formula: 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Li, Wenjing; Yin, Changzhen; Yang, Xiao; Liu, Hailong; Zheng, Xueli; Yuan, Maolin; Li, Ruixiang; Fu, Haiyan; Chen, Hua published an article in 2017, the title of the article was Cu(II)-Mediated keto C(sp3)-H bond 伪-acyloxylation of N,N-dialkylamides with aromatic carboxylic acids.Safety of N,N-Diethylacetamide And the article contains the following content:

The selective oxidative coupling of aromatic carboxylic acids with the C(sp3)-H bond adjacent to the keto group of alkylamides was developed by employing a low cost copper source. This provides an efficient approach for synthesis of O-benzoylglycolamides. The protocol displayed good functional group tolerance. A broad range of benzoic acids directly coupled with alkylamides to afford a variety of O-benzoylglycolamides in moderate to good yields. In addition, a reasonable radical mechanism was proposed based on EPR experiments The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Safety of N,N-Diethylacetamide

The Article related to copper catalyst acyloxylation dialkylamide aromatic carboxylic acid, benzoylglycolamide preparation, General Organic Chemistry: Synthetic Methods and other aspects.Safety of N,N-Diethylacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 1, 2020, Yoo, Kwangho; Lee, Jooyeon; Park, Myung Hwan; Kim, Youngjo; Kim, Hyun Jin; Kim, Min published an article.Formula: C13H12N2O The title of the article was Ir-Catalyzed C-H Amidation Using Carbamoyl Azides for the Syntheses of Unsymmetrical Ureas. And the article contained the following:

An iridium-catalyzed C-H amidation for the syntheses of unsym. urea was developed using carbamoyl azides (R(R’)N-C(O)-N3) as the nitrogen source. A combination of iridium and silver gave an active catalyst for C-N bond formation. A variety of urea derivatives were synthesized using carbamoyl azides with only dinitrogen byproducts. Finally, the use of the transient directing group strategy with carbamoyl azides extended the substrate scope of the catalytic C-H amidation to yield aldehyde-containing unsym. ureas. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Formula: C13H12N2O

The Article related to carbamoyl azide benzamide directing group iridium silver catalyst amidation, unsym urea preparation, General Organic Chemistry: Synthetic Methods and other aspects.Formula: C13H12N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On November 30, 2021, Han, Bo; Zhang, Jiong; Jiao, Haijun; Wu, Lipeng published an article.SDS of cas: 685-91-6 The title of the article was Zirconium-hydride-catalyzed site-selective hydroboration of amides for the synthesis of amines: Mechanism, scope, and application. And the article contained the following:

The selective hydroboration of primary, secondary, and tertiary amides at room temperature catalyzed by an earth-abundant-metal catalyst, Zr-H, for accessing diverse amines was reported. Various readily reducible functional groups, such as esters, alkynes, and alkenes, were well tolerated. Furthermore, the methodol. was extended to the synthesis of bio- and drug-derived amines. Detailed mechanistic studies revealed a reaction pathway entailing aldehyde and amido complex formation via an unusual C-N bond cleavage-reformation process, followed by C-O bond cleavage. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).SDS of cas: 685-91-6

The Article related to amide zirconium hydride catalyst regioselective hydroboration, amine preparation reaction mechanism, General Organic Chemistry: Synthetic Methods and other aspects.SDS of cas: 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 5, 2021, Wang, Xia; Yang, Peng; Hu, Bo; Zhang, Qian; Li, Dong published an article.SDS of cas: 102-07-8 The title of the article was Hypervalent Iodine Reagent-Promoted Hofmann-Type Rearrangement/Carboxylation of Primary Amides. And the article contained the following:

A novel transformation of primary amides RC(O)NH2 (R = Ph, thiophen-2-yl, Bu, cyclopropyl, etc.) to secondary amides RNHC(O)R1 (R1 = methyltrifluoromethyl, Et, Ph, etc.) promoted by hypervalent iodine reagents Ph(I)(OC(O)R1)2 was developed. The hypervalent iodine reagent-mediated Hofmann-type rearrangement generated an isocyanate intermediate, which was subsequently trapped by an in situ generated carboxylic acid from the hypervalent iodine reagent to provide the corresponding secondary amides. This method provided a facile and efficient route for the synthesis of secondary amides from primary amides and also revealed novel reactivities of hypervalent iodine reagents. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).SDS of cas: 102-07-8

The Article related to secondary amide preparation, primary amide hypervalent iodine reagent hofmann rearrangement carboxylation, General Organic Chemistry: Synthetic Methods and other aspects.SDS of cas: 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On April 16, 2021, Luo, Zhongli; Imamura, Kenji; Shiota, Yoshihito; Yoshizawa, Kazunari; Hisaeda, Yoshio; Shimakoshi, Hisashi published an article.Computed Properties of 685-91-6 The title of the article was One-Pot Synthesis of Tertiary Amides from Organic Trichlorides through Oxygen Atom Incorporation from Air by Convergent Paired Electrolysis. And the article contained the following:

A convergent paired electrolysis catalyzed by a B12 complex for the one-pot synthesis of a tertiary amide from organic trichlorides has been developed. Various readily available organic trichlorides, such as benzotrichloride and its derivatives, chloroform, dichlorodiphenyltrichloroethane (DDT), trichloro-2,2,2-trifluoroethane (CFC-113a), and trichloroacetonitrile (CNCCl3), were converted to amides in the presence of tertiary amines through oxygen incorporation from air at room temperature The amide formation mechanism in the paired electrolysis, which was mediated by a cobalt complex, was proposed. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Computed Properties of 685-91-6

The Article related to tertiary amide one pot synthesis chemoselective, organic trichloride tertiary amine paired electrolysis air, General Organic Chemistry: Synthetic Methods and other aspects.Computed Properties of 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics