Month: November 2022

On January 7, 2020, Lou, Yao-Yin; Hapiot, Philippe; Floner, Didier; Fourcade, Florence; Amrane, Abdeltif; Geneste, Florence published an article.Related Products of 79-07-2 The title of the article was Efficient Dechlorination of α-Halocarbonyl and α-Haloallyl Pollutants by Electroreduction on Bismuth. And the article contained the following:

The electrocatalytic activity of bismuth considered as a low-cost and green electrode material was studied in reductive dechlorination processes. Cyclic voltammetry analyses showed that the Bi electrode exhibited a high catalytic activity to reduce alachlor, a chlorinated herbicide, in the aqueous medium at different pH values. Bulk electrolyzes were performed at different potentials and pH values. Alachlor was reduced in deschloroalachlor, its dechlorinated derivative, with a high selectivity (96%) and a current efficiency of 48%. The reductive dechlorination of other chlorinated compounds with an activated carbon atom was then studied, showing that the bismuth electrode catalyzed the electroreduction of chloroacetamides, α-halocarbonyl, and α-haloallyl pollutants. Cyclic voltammetry experiments allowed us to propose a mechanism explaining the high catalytic activity of bismuth to reduce these families of compounds The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Related Products of 79-07-2

The Article related to bismuth electrocatalytic reduction dechlorination organohalogen pollutant wastewater, Waste Treatment and Disposal: Chemical Treatment Of Aqueous Wastes and other aspects.Related Products of 79-07-2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Wu, Chenggui; Cheng, Hong-Gang; Chen, Ruiming; Chen, Han; Liu, Ze-Shui; Zhang, Jingyang; Zhang, Yuming; Zhu, Yuxin; Geng, Zhi; Zhou, Qianghui published an article in 2018, the title of the article was Convergent syntheses of 2,3-dihydrobenzofurans via a Catellani strategy.COA of Formula: C11H9NO3 And the article contains the following content:

A cooperative catalytic system comprising a Pd/XPhos complex and a potassium salt of 5-norbornene-2-carboxylic acid to promote the annulation between aryl iodides and epoxides was developed, thereby providing highly convergent access to valuable 2,3-dihydrobenzofuran (DHBF) scaffolds. The unique potassium salt of the inexpensive 5-norbornene-2-carboxylic acid serves as a highly efficient catalytic mediator (10 mol%), which leads to fewer side reactions. The salient features of the reaction include its broad substrate scope (with respect to both aryl iodides and epoxides), its high atom economy and good chemo-selectivity. Furthermore, no extra base is needed for the process. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).COA of Formula: C11H9NO3

The Article related to dihydrobenzofuran preparation, aryl iodide epoxide annulation palladium norbornene carboxylic acid catalyst, Heterocyclic Compounds (One Hetero Atom): Areno- and Diarenofurans and other aspects.COA of Formula: C11H9NO3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Amaral, Miriam C. S.; Moravia, Wagner G.; Lange, Lisete C. published an article in 2017, the title of the article was Characterization of residual organic compounds of aerobic degradation of landfill leachate.Synthetic Route of 685-91-6 And the article contains the following content:

The purpose of this article is to characterize and compare the residual COD of raw landfill leachate and its low and high mol. weight fractions before and after aerobic degradation process. The low and high mol. weight fractions (<10 kDa and >10 kDa, resp.) were obtained by the use of an ultrafiltration cell. Samples of the fractions with mol. weights 10 kDa, as well as the raw leachate, were characterized in terms of COD, protein, carbohydrate and lipid concentration and by biodegradability test. The compound identification of all samples was carried out using gas chromatog. coupled with mass spectrometry (GC/MS). The results show that the landfill leachate studied is constituted of approx. 60% of compounds with mol. weight <10 kDa. Approx. 80% of the compounds identified in the leachate had been degraded. This is an indication that most of the compounds that constitute the significant fraction of residual COD correspond to intermediate products and products of condensation of affluent compounds or had been generated during the degradation (SMP). Similar compounds were identified in all effluents of the degradation assay, suggesting the presence of SMP. These compounds, predominantly aliphatic and esters, are characterized by high mol. weight and probable refractory nature. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Synthetic Route of 685-91-6

The Article related to residual organic compound aerobic degradation landfill leachate, compounds identifications, smp, leachate, residual cod, Waste Treatment and Disposal: Chemical Treatment Of Aqueous Wastes and other aspects.Synthetic Route of 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 20, 2021, Zhang, Di; Dong, Shengkun; Zhang, Aihong; Chen, Li; Yu, Zhenxun; Wang, Qi; Chu, Wenhai published an article.Reference of 2-Chloroacetamide The title of the article was Catalytic hydrolysis: A novel role of zero-valent iron in haloacetonitrile degradation and transformation in unbuffered systems. And the article contained the following:

Efforts to remove highly toxic haloacetonitriles (HANs) is an important step to reduce health risks associated with disinfection by product exposure. Zero valent iron (ZVI) is a versatile material, whose reductant, sorbent and coagulant role has been well understood. However, their catalytic role is less known. In this study, the degradation and transformation of HANs in ZVI system were investigated. Significant decreases of the four HANs in ZVI system were observed, and haloacetamides and haloacetic acids (hydrolysis products of HANs) were the dominant transformation products of HANs. However dehalogenated HANs, Fe (II) and Fe (III) were rarely detected after reaction, indicating that the ZVI acted as a catalyst to promote the hydrolysis of HANs, rather than other previously reported causes (dehalogenation or redox reaction). The HAN degradation rates were dramatically affected by the initial pH, ZVI doses and initial HAN concentration Kinetic anal. indicated that HAN removal was enhanced with the increase of initial pH (5-9), ZVI doses (1-10 g/L), and initial HAN concentration (25-200μg/L). ZVI induced the transformation of HANs to haloacetamides, haloacetic acids and other de-halogenated compounds, which reduced the cytotoxicity and genotoxicity by 88% and 85%, resp. This study helped to understand the fate of HAN during the transmission in cast iron pipes, and provided a theor. foundation for future HAN control and monitoring efforts. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Reference of 2-Chloroacetamide

The Article related to haloacetonitrile degradation catalytic hydrolysis iron, catalytic hydrolysis, dbp control, disinfection by-products, zero-valent iron, Waste Treatment and Disposal: Chemical Treatment Of Aqueous Wastes and other aspects.Reference of 2-Chloroacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 31, 2022, Zhi, Suli; Zhou, Jing; Zhang, Zulin; Zhang, Keqiang published an article.Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Determination of 38 antibiotics in raw and treated wastewater from swine farms using liquid chromatography-mass spectrometry. And the article contained the following:

The present study firstly aimed at developing a multi-residue method to identify and quantify 38 veterinary antibiotics (belonging to five different classes) not only for raw swine wastewater but also for wastewater differently treated by different units. The proposed method is based on a solid-phase extraction procedure and ultra high performance liquid chromatog. with mass spectrometry. For sample preparation, the optimal loading sample volume was selected as 50 mL, the pH of which was adjusted to approx. 3.0 using formic acid. Then 0.1 g/L EDTA disodium salt was added. The recovery rates for different types of wastewaters were in the range of 35.94-124.51% and the relative standard deviations were in the range of 0.36-14.62%. All the matrix standard curves exhibited high linearity (0.9956-0.9999). The matrix effects for the target antibiotics ranged from -61.73 to +148.75%. To ensure the practicality of the method, we performed the detection of the actually added concentration to determine method detection limits and quantitation limits. The quantitation limits of most of the target antibiotics were 0.04μg/L, except for spiramycin (0.1μg/L) and roxithromycin (0.2μg/L). This optimized and validated method was applied to analyze antibiotic residues in swine water samples from four swine farms. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to swine farms wastewater antibiotic liquid chromatog mass spectrometry, solid-phase extraction, swine wastewater, veterinary antibiotics, Waste Treatment and Disposal: Physical Treatment Of Aqueous Wastes and other aspects.Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Sun, Bo; Liu, Xiaowen; Zheng, Xu; Wang, Changyuan; Meng, Qiang; Sun, Huijun; Shu, Xiaohong; Liu, Kexin; Sun, Xiuli; Li, Yanxia; Ma, Xiaodong published an article in 2020, the title of the article was Novel Pyrimidines as Multitarget Protein Tyrosine Kinase Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis (IPF).Recommanded Product: 16230-24-3 And the article contains the following content:

A new class of pyrimidine derivatives were identified as potent protein tyrosine kinase (PTK) inhibitors for the treatment of idiopathic pulmonary fibrosis (IPF). Most of these small-mol. inhibitors displayed strong enzymic activity against BTK and JAK3 kinases at concentrations lower than 10 nM. The representative compound N-(3-((5-chloro-2-(4-((1-morpholino)acetylamino)phenylamino)-4-pyrimidinyl)amino)phenyl)acrylamide (6 a) also exhibited high inhibitory potency toward both BTK and JAK kinase families, as well as ErbB4, at a concentration of 10 nM, achieving rates of inhibition higher than 57%. Addnl., in vivo biol. evaluations showed that 6 a can remarkably decrease the severity of IPF disease. All these investigations suggested that the multi-PTK inhibitor 6 a may serve as a promising agent for the treatment of IPF. The experimental process involved the reaction of N-(3-Aminophenyl)acrylamide(cas: 16230-24-3).Recommanded Product: 16230-24-3

The Article related to pyrimidine derivative preparation tyrosine kinase inhibitor idiopathic pulmonary fibrosis, ipf, ptk, inhibitors, multitarget, pyrimidine, Pharmacology: Effects Of Inflammation Inhibitors and Immune Agents and other aspects.Recommanded Product: 16230-24-3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 31, 2021, Camargo-Perea, Ana L.; Serna-Galvis, Efraim A.; Lee, Judy; Torres-Palma, Ricardo A. published an article.Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Understanding the effects of mineral water matrix on degradation of several pharmaceuticals by ultrasound: Influence of chemical structure and concentration of the pollutants. And the article contained the following:

Degradation of seven relevant pharmaceuticals with different chem. structures and properties: acetaminophen (ACE), cloxacillin (CXL), diclofenac (DCF), naproxen (NPX), piroxicam (PXC), sulfacetamide (SAM) and cefadroxil (CDX), in distilled water and mineral water by ultrasound was studied herein. Firstly, proper conditions of frequency and acoustic power were determined based on the degradation ability of the system and the accumulation of sonogenerated hydrogen peroxide (24.4 W and 375 kHz were found as the suitable conditions for the sonochem. treatment of the pharmaceuticals). Under such conditions, the pharmaceuticals degradation order in distilled water was: PXC > DCF ∼ NPX > CXL > ACE > SAM > CDX. In fact, the initial degradation rate showed a good correlation with the Log P parameter, most hydrophobic compounds were eliminated faster than the hydrophilic ones. Interestingly, in mineral water, the degradation of those hydrophilic compounds (i.e., ACE, SAM and CDX) was accelerated, which was attributed to the presence of bicarbonate ions. Afterwards, mineral water containing six different initial concentrations (i.e., 0.331, 0.662, 3.31, 16.55, 33.1, and 331μM) of selected pharmaceuticals was sonicated, the lowest concentration (0.331μM) always gave the highest degradation of the pollutants. This result highlights the great ability of the sonochem. process to treat bicarbonate-rich waters containing pollutants at trace levels, as pharmaceuticals. Finally, the addition of ferrous ions to the sonochem. system to generate a sono-Fenton process resulted in an acceleration of degradation in distilled water but not in mineral water. This was attributed to the scavenging of sonogenerated HO• by bicarbonate anion, which decreases H2O2 accumulation, thus limiting the Fenton reaction. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to mineral water pollutant degradation pharmaceutical ultrasound, bicarbonate effect, carbonate radical, mineral water, pharmaceuticals, sonochemistry, Waste Treatment and Disposal: Chemical Treatment Of Aqueous Wastes and other aspects.Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 15, 2020, Zhu, Yanming; Zheng, Xu; Wang, Changyuan; Sun, Xiuli; Sun, Huijun; Ma, Tengyue; Li, Yanxia; Liu, Kexin; Chen, Lixue; Ma, Xiaodong published an article.Product Details of 16230-24-3 The title of the article was Synthesis and biological activity of thieno[3,2-d]pyrimidines as potent JAK3 inhibitors for the treatment of idiopathic pulmonary fibrosis. And the article contained the following:

Idiopathic pulmonary fibrosis (IPF) is a serious and fatal lung disease, with a median survival of only 3-5 years from diagnosis. Janus kinase 3 (JAK3) has a well-established role in the pathogenesis of various autoimmune diseases, including rheumatoid arthritis (RA) and autoimmune-related pulmonary fibrosis. In this study, through the use of a conformationally-constrained design strategy, a series of thieno[3,2-d]pyrimidines were synthesized as potent JAK3 inhibitors for the treatment of IPF. Among them, the most potent JAK3 inhibitor, namely 8e (IC50 = 1.38 nM), significantly reduced the degree of airsacculitis and fibrosis according to hematoxylin-eosin (HE) staining assay for the lung tissue in the bleomycin (BLM)-induced pulmonary fibrosis mouse model. The clear reduction of the lung collagen deposition by the determination of Masson and hydroxyproline (HYP) content also demonstrated its efficacy in the treatment of fibrosis. In addition, 8e also reduced the expression of the inflammatory markers IL-6, IL-17A, TNF-α and malondialdehyde (MDA) in lung tissue, which indicated its higher anti-inflammatory activity compared with that of the reference agents (nintedanib and gefitinib). Furthermore, it possessed low cytotoxicity against normal human bronchial epithelia (HBE) cells (IC50 > 39.0μM) and C57BL mice. All these evaluated biol. properties suggest that 8e may be a potential JAK3 inhibitor for the treatment of IPF. The experimental process involved the reaction of N-(3-Aminophenyl)acrylamide(cas: 16230-24-3).Product Details of 16230-24-3

The Article related to thieno pyrimidine derivative preparation jak3 inhibitors idiopathic pulmonary fibrosis, idiopathic pulmonary fibrosis, jak inhibitors, thieno[3,2-d]pyrimidines, Pharmacology: Effects Of Inflammation Inhibitors and Immune Agents and other aspects.Product Details of 16230-24-3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 31, 2013, Karimi Zarchi, Mohammad Ali; Tarabsaz, Ali published an article.Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione The title of the article was Versatile and efficient method for synthesis of β-halohydrins via regioselective ring opening reaction of epoxides using cross-linked poly (4-vinylpyridine) supported HCl and HBr under solvent-free conditions. And the article contained the following:

In this paper a versatile and efficient method for synthesis of vicinal halohydrins via regioselective ring opening of epoxides by using polymer-supported HCl and HBr under solvent-free conditions is described. The regioselective ring opening of various epoxides is achieved under mild and solvent-free conditions by using crosslinked poly(4-vinylpyridine)-supported hydrochloric acid, [P4-VP]HCl and crosslinked poly(4-vinylpyridine)-supported hydrobromic acid, [P4-VP]HBr, under heterogeneous conditions. [P4-VP]HCl and [P4-VP]HBr act as both solid proton source and as nucleophile and consequently, the corresponding β-halohydrin product is prepared [P4-VP]HCl and [P4-VP]HBr can be easily regenerated and reused several cycles without their activity changing appreciably. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

The Article related to vinylpyridine polymer hydrobromide hydrochloride catalyst ring opening epoxide, halohydrin production vinylpyridine polymer hydrobromide hydrochloride catalyst, Plastics Manufacture and Processing: Chemical Properties Of Resins and other aspects.Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 31, 2021, Wang, Guoying; Li, Guoxue; Chang, Jiali; Kong, Yilin; Jiang, Tao; Wang, Jiani; Yuan, Jing published an article.Recommanded Product: 144-80-9 The title of the article was Enrichment of antibiotic resistance genes after sheep manure aerobic heap composting. And the article contained the following:

In this study, physio-chem. properties, 45 antibiotics, 6 heavy metals, 42 antibiotic resistance genes (ARGs), 3 mobile genetic elements, and the bacterial community structure were investigated to analyze the fate of ARGs during sheep manure aerobic heap composting. Results showed that sheep manure heap composting could produce mature compost. The degradation processes reduced the total antibiotics content by 85%. The abundance of ARGs and mobile genetic elements (MGEs) were enriched 9-fold, with the major increases to sul and tet genes (sulI, sulII, tetQ, and tetX). Tetracycline and sulfonamide resistance genes were the most abundant ARGs after composting (more than 88% of all genes). The genes tetA, tetX and sulI were related to the most diverse bacteria that were most able to proliferate during heap composting. Therefore, sulI and tetX are the major ARGs to be controlled, and Actinobacteria and Bacteroidetes may be the major host bacteria. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Recommanded Product: 144-80-9

The Article related to antibiotic resistance gene sheep manure aerobic heap composting, antibiotic, antibiotic resistance genes, bacterial community structures, heap composting, sheep manure, Waste Treatment and Disposal: Physical Treatment Of Aqueous Wastes and other aspects.Recommanded Product: 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics