Month: November 2022

Krais, Annette M.; Essig, Julie Y.; Gren, Louise; Vogs, Carolina; Assarsson, Eva; Dierschke, Katrin; Nielsen, Joern; Strandberg, Bo; Pagels, Joakim; Broberg, Karin; Lindh, Christian H.; Gudmundsson, Anders; Wierzbicka, Aneta published an article in 2021, the title of the article was Biomarkers after controlled inhalation exposure to exhaust from Hydrogenated vegetable oil (HVO).Recommanded Product: 27115-50-0 And the article contains the following content:

Hydrogenated vegetable oil (HVO) is a renewable diesel fuel used to replace petroleum diesel. The organic compounds in HVO are poorly characterized; therefore, toxicol. properties could be different from petroleum diesel exhaust. The aim of this study was to evaluate the exposure and effective biomarkers in 18 individuals after short-term (3 h) exposure to HVO exhaust and petroleum diesel exhaust fumes. Liquid chromatog. tandem mass spectrometry was used to analyze urinary biomarkers. A proximity extension assay was used for the measurement of inflammatory proteins in plasma samples. Short-term (3 h) exposure to HVO exhaust (PM1 ~1μg/m3 and ~90μg/m3 for vehicles with and without exhaust aftertreatment systems, resp.) did not increase any exposure biomarker, whereas petroleum diesel exhaust (PM1 ~300μg/m3) increased urinary 4-MHA, a biomarker for p-xylene. HVO exhaust from the vehicle without exhaust aftertreatment system increased urinary 4-HNE-MA, a biomarker for lipid peroxidation, from 64 ng/mL urine (before exposure) to 141 ng/mL (24 h after exposure, p < 0.001). There was no differential expression of plasma inflammatory proteins between the HVO exhaust and control exposure group. In conclusion, short-term exposure to low concentrations of HVO exhaust did not increase urinary exposure biomarkers, but caused a slight increase in lipid peroxidation associated with the particle fraction. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Recommanded Product: 27115-50-0

The Article related to hydrogenated vegetable oil inhalation exposure biomarker, hvo, aerosol, biomarkers, exposure studies, lipid peroxidation, renewable diesel, Fossil Fuels, Derivatives, and Related Products: Crude-Oil Refining and other aspects.Recommanded Product: 27115-50-0

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 31, 2020, Baulina, T. V.; Kudryavtsev, I. Yu.; Artem’ev, A. V.; Bagryanskaya, I. Yu.; Pasechnik, M. P.; Brel, V. K. published an article.Reference of 2-Chloroacetamide The title of the article was Synthesis, Molecular, and Crystal Structure of Tris(2-carbamoylmethoxyphenyl)phosphine Oxide. And the article contained the following:

New tripodal ligand, tris(2-carbamoylmethoxyphenyl)phosphine oxide (I), has been synthesized via the alkylation of tris(2-hydroxyphenyl)phosphine oxide with chloroacetamide. The ligand structure has been studied by means of IR and NMR (1H, 31P) spectroscopy as well as X-ray diffraction. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Reference of 2-Chloroacetamide

The Article related to tris carbamoylmethoxyphenyl phosphine mol structure oxide, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Reference of 2-Chloroacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On April 19, 2017, Ma, Xiaodong; Ge, Yang; Song, Zhendong; Huang, Shanshan; Wang, Changyuan; Zhang, Jianbin; Tang, Zeyao; Liu, Kexin published a patent.Application In Synthesis of N-(3-Aminophenyl)acrylamide The title of the patent was Phosphoryl pyrimidine compound, and its composition and application. And the patent contained the following:

The title phosphoryl pyrimidine compound is shown in formula I, wherein, X is Cl or F; L is -CH2- or -O(CH2)2CH2-; R1 is selected from H, Me, methoxy, and Cl; R2 is selected from methoxy, ethoxy, etc.; R3 is methoxy, ethoxy, etc. The phosphoryl pyrimidine compound is capable of inhibiting Brutons tyrosine kinase, so as to treat tumor diseases, such as Burkitts lymphoma, diffuse large B cell lymphoma, follicular lymphoma, and chronic lymphocytic leukemia. The experimental process involved the reaction of N-(3-Aminophenyl)acrylamide(cas: 16230-24-3).Application In Synthesis of N-(3-Aminophenyl)acrylamide

The Article related to phosphoryl pyrimidine compound preparation antitumor activity, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Application In Synthesis of N-(3-Aminophenyl)acrylamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 15, 2022, Wang, Zheng; Li, Mengxiao; Liao, Yufeng; Pan, Yang; Shuang, Chendong; Li, Jun; Zhou, Qing; Li, Aimin published an article.Reference of 2-Chloroacetamide The title of the article was Formation of disinfection byproducts from chlorinated soluble microbial products: Effect of carbon sources in wastewater denitrification processes. And the article contained the following:

Carbon sources are crucial for biol. denitrification in wastewater treatment that significantly affects the production of soluble microbial products (SMPs), thereby affecting the formation of disinfection byproducts (DBPs) during subsequent chlorination. However, the effect of carbon sources on DBPs formation has not been studied. In this work, sodium acetate, sodium lactate, and glucose were used as carbon sources, and denitrifying SMPs derived from different carbon sources were used as DBPs precursors to investigate the formation potential (FP) of 16 carbonaceous DBPs and 19 nitrogenous DBPs. Results showed that the carbonaceous DBPs FP of SMPs derived from acetate, lactate, and glucose were 502.1-584.3, 250.3-288.9, and 374.7-439.1μg/L, resp., and the nitrogenous DBPs FP were 19.1-45.6, 12.8-21.9, and 7.9-9.0μg/L, resp. After chlorination, the genotoxicity of SMPs measured by the SOS/umu test was also evaluated with 364 ng 4-NQO/L for acetate, 212 ng 4-NQO/L for lactate, and 138 ng 4-NQO/L for glucose. Based on XPS, chem. structures of SMPs were characterized, and their relationship with DBPs FP was investigated to explain the mechanism of DBPs formation. Aromatic C and C-O were found to be the major precursor structures to form carbonaceous DBPs, and their lowest proportions in lactate-derived SMPs caused the lowest carbonaceous DBPs FP. Organic nitrogen, including aromatic N, amide/peptide N, and primary amine N, was the precursor of nitrogenous DBPs. The lowest concentration of dissolved organic nitrogen for glucose-derived SMPs caused the lowest nitrogenous DBPs FP and genotoxicity. Glucose may be a better choice among the three carbon sources in terms of reducing genotoxicity. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Reference of 2-Chloroacetamide

The Article related to carbon disinfection byproduct denitrification wastewater treatment, Waste Treatment and Disposal: Biological Treatment Of Aqueous Wastes and other aspects.Reference of 2-Chloroacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 30, 2022, Pu, Miao; Ailijiang, Nuerla; Mamat, Anwar; Chang, Jiali; Zhang, Qiongfang; Liu, Yifan; Li, Nanxin published an article.Name: N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Occurrence of antibiotics in the different biological treatment processes, reclaimed wastewater treatment plants and effluent-irrigated soils. And the article contained the following:

Reclaimed wastewater is increasingly being used for agricultural irrigation to address water scarcity, particularly in arid and semiarid areas. In this study, the occurrence and removal of 24 antibiotics were investigated in two wastewater treatment systems (WWTSs) and their irrigation areas located in the arid northwestern region of China. The different WWTSs included absorption-biodegradation (AB) + anaerobic-anoxic-oxic (AAO) and AAO + AAO + membrane bioreactor (MBR). Nineteen antibiotics were detected, with concentrations ranging from low to 60.8μg/L. The dominant antibiotic classes were quinolones (QNs) and macrolides (MLs) in winter, and MLs and sulfonamides (SAs) in summer. The AAO + AAO + MBR system exhibited better removal efficiencies for most antibiotics, improving their adsorption and biodegradation Except for ofloxacin (OFC) and norfloxacin (NFC), the concentrations of the detected antibiotics were higher in summer than in winter. However, the antibiotic removal efficiency increased by 2-141% in summer compared to winter due to the increase in microbial activity with temperature Even though reclaimed treatment water plants contributed to the removal of antibiotics, residual antibiotics still affected the soil environment after green irrigation. In irrigated soil, QNs were predominantly detected, with a maximum concentration of 150.9 ng/kg for NFC. An ecol. risk assessment showed that OFC, NFC, enrofloxacin, and lomefloxacin presented low or medium ecol. risks in at least two irrigated sites. Thus, more attention should be given to the reuse of reclaimed wastewater, as it may pose toxicity risks to organisms in the soil environment. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Name: N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to antibiotics biol process reclaimed wastewater treatment plant soil, Waste Treatment and Disposal: Biological Treatment Of Aqueous Wastes and other aspects.Name: N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 25, 2019, Zhou, Qilin; Zhang, Fenghua; Xie, Jianhua; Wang, Lixin published a patent.Related Products of 65645-88-7 The title of the patent was Chiral spiro phosphine-amino-oxazoline tridentate ligand, its preparation method and application. And the patent contained the following:

A chiral spiro phosphine-amino-oxazoline tridentate ligand having ruthenium complex exhibits high catalytic activity (TON to 10,000) and enantioselectivity (up to 98% ee) in the asym. hydrogenation of α-ketoamide, which has practical value is provided. The chiral spiro phosphine-amino-oxazoline tridentate ligand comprises a compound of formula I or an enantiomer, racemate, or a catalytically acceptable salt thereof, and having a main structural feature of having a chiral spiroindoline skeleton and having a chiral oxazoline group. The method for preparing a chiral spiro phosphine-amino-oxazoline tridentate ligand by racemic or optically active 7-diaryl/alkylphosphino-7/-aminospiroindole represented by formula 1 having a chiral spiroindoline skeleton used as a starting material. The chiral spiro phosphine-amino-oxazoline tridentate ligand forms a complex with the transition metal salt and can be used to catalyze the asym. catalytic hydrogenation of the carbonyl compound The experimental process involved the reaction of (S)-2-Hydroxy-N-methyl-2-phenylacetamide(cas: 65645-88-7).Related Products of 65645-88-7

The Article related to chiral spiro phosphine amino oxazoline preparation enantioselective hydrogenation catalyst, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Related Products of 65645-88-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On November 20, 2020, Fernandez-Perez, Hector; Lenartowicz, Pawel; Carreras, Lucas; Grabulosa, Arnald; Kafarski, Pawel; Vidal-Ferran, Anton published an article.Quality Control of 2-Chloroacetamide The title of the article was Access to α-Aminophosphonic Acid Derivatives and Phosphonopeptides by [Rh(P-OP)]-Catalyzed Stereoselective Hydrogenation. And the article contained the following:

The hydrogenation of N-substituted vinylphosphonates using rhodium complexes derived from P-OP ligands L1, ent-L1 or (R,R)-Me-DuPHOS as catalysts has been successfully accomplished, achieving very high levels of stereoselectivity (up to 99% ee or de). The described synthetic strategy allowed for the efficient preparation of alpha-aminophosphonic acid derivatives, e.g. I, and phosphonopeptides, e.g. II, which are valuable building blocks for the preparation of biol. relevant mols. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Quality Control of 2-Chloroacetamide

The Article related to vinyl phosphonate rhodium catalyst hydrogenation mol structure, alpha aminophosphonic acid phophonopeptide asym preparation, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Quality Control of 2-Chloroacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 31, 2021, Wang, Juan; Zhang, Peng-Li; Ansari, Mohammad Fawad; Li, Shuo; Zhou, Cheng-He published an article.COA of Formula: C8H10N2O3S The title of the article was Molecular design and preparation of 2-aminothiazole sulfanilamide oximes as membrane active antibacterial agents for drug resistant Acinetobacter baumannii. And the article contained the following:

A series of 2-aminothiazole sulfanilamide oximes were developed as new membrane active antibacterial agents to conquer the microbial infection. Benzoyl derivative 10c was preponderant for the treatment of drug-resistant A. baumannii infection in contrast to norfloxacin and exerted excellent biocompatibility against mammalian cells including erythrocyte and LO2 cell line. Meanwhile, it had ability to eradicate established biofilm to alleviate the resistance burden. Mechanism investigation elucidated that compound 10c was able to disturb the membrane effectively and inhibit lactic dehydrogenase, which led to cytoplasmic content leakage. The cellular redox homeostasis was interfered via the production of reactive oxygen and nitrogen species (RONS), which further contributed to respiratory pathway inactivation and reduction of GSH activity. This work indicated that 2-aminothiazole sulfanilamide oximes could be a promising start for the exploitation of novel antibacterial agents against pathogens. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).COA of Formula: C8H10N2O3S

The Article related to acinetobacter aminothiazole sulfanilamide oxime antibacterial mol design, a. baumannii, aminothiazole, antibacterial, oxime, sulfanilamide, Microbial, Algal, and Fungal Biochemistry: Antimicrobial Sensitivity and other aspects.COA of Formula: C8H10N2O3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yang, Tianlong; Lu, Maojian; Lin, Zhaowei; Huang, Mingqiang; Cai, Shunyou published an article in 2019, the title of the article was Visible-light-promoted oxidation/condensation of benzyl alcohols with dialkylacetamides to cinnamides.Reference of N,N-Diethylacetamide And the article contains the following content:

Oxidative cross-coupling reactions of benzyl alcs. with N,N-dialkylacetamides were developed only employing oxygen as the terminal oxidant, efficiently providing a new, novel protocol for the construction of multifunctionalized cinnamides with the synergistic effects of KOH, organic photocatalyst eosin Y, and visible light irradiation at room temperature A broad substrate scope and mild reaction conditions are the prominent features of this transformation. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Reference of N,N-Diethylacetamide

The Article related to cinnamide preparation visible light promoted oxidation condensation reaction, oxidative cross coupling benzyl alc diarylacetamide organic photocatalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: General and other aspects.Reference of N,N-Diethylacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 15, 2021, Sakurai, Karen Sayuri Ito; Pompei, Caroline Moco Erba; Tomita, Ines N.; Santos-Neto, Alvaro J.; Silva, Gustavo Henrique Ribeiro published an article.Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Hybrid constructed wetlands as post-treatment of blackwater: An assessment of the removal of antibiotics. And the article contained the following:

New sanitation systems have been developed to treat, recover energy and nutrients, and permit reuse processes at the source of generation, minimizing water use and flow segregation. Thus, this study was carried out with the objective of evaluating the potential of hybrid constructed wetlands in the removal of organic matter, nutrients, pathogenic microorganisms, and 12 antibiotics from blackwater previously treated by an upflow anaerobic sludge blanket reactor. A hybrid system of constructed wetlands was used, comprised of a horizontal subsurface flow constructed wetland with a total volume of 0.60 m3 followed by a vertical subsurface flow constructed wetland with a total volume of 0.20 m3. Three different hydraulic retention times were comparatively tested (1.0, 2.0, and 3.0 days for the horizontal subsurface flow constructed wetland, and 1.1, 0.9, and 0.4 days for the vertical subsurface flow constructed wetland) in four distinct stages. The plant species used was Canna generalis. The results from this study demonstrate the potential of constructed wetlands as a suitable technol. for post-treatment of segregated domestic wastewater (anaerobically-digested blackwater). Efficient reduction of COD, BOD5, total nitrogen, and total phosphorus (74, 93, 50, and 61%, resp.) was achieved, with a hydraulic retention time of 3.0 and 1.1 days for horizontal and vertical subsurface flow constructed wetland, resp. (stage IV). The presence of ciprofloxacin was confirmed by chromatog. and mass spectrometric anal. in an average concentration of 442.6 ng. L-1 at the inflow of the horizontal subsurface flow constructed wetland, but was not observed at the outflow. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to ciprofloxacin canna phragmites anaerobic sludge blanket reactor, antibiotics removal, blackwater, hybrid constructed wetlands, new sanitation, post-treatment, Waste Treatment and Disposal: Biological Treatment Of Aqueous Wastes and other aspects.Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics