Month: November 2022

On May 7, 2020, Koopmans, Carsten; Laemmerhold, Kai; Guertler, Christoph; Frick-Delaittre, Elena; Wolf, Aurel; Simon, Joachim; Wang, Min; Thiel, Daniel; Leitner, Walter published a patent.Related Products of 5455-98-1 The title of the patent was Production of thermoplastic polyoxazolidinone polymers and thermoplastic polyoxazolidinone. And the patent contained the following:

A process for producing thermoplastic polyoxazolidinone, comprising (i) reaction of a diisocyanate compound (A) with a bisepoxide compound (B) in the presence of a catalyst (C) and a compound (D) in a solvent (E) forming an intermediate compound (F) and (ii) reaction of a compound (G) with the intermediate (F) formed in step (i), where the bisepoxide compound (B) comprises isosorbide diglycidyl ether, where compound (D) is ≥1 compounds selected from monofunctional isocyanate and monofunctional epoxide, and where compound (G) is an alkylene oxide. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Related Products of 5455-98-1

The Article related to thermoplastic polyoxazolidinone polymer, Chemistry of Synthetic High Polymers: Organic Addition Polymerization and other aspects.Related Products of 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Jacquet, Emmanuel; Alard, Olivier; Gounelle, Matthieu published an article in 2015, the title of the article was The formation conditions of enstatite chondrites: Insights from trace element geochemistry of olivine-bearing chondrules in Sahara 97096 (EH3).SDS of cas: 97-09-6 And the article contains the following content:

We report in situ LA-ICP-MS trace element analyses of silicate phases in olivine-bearing chondrules in the Sahara 97096 (EH3) enstatite chondrite. Most olivine and enstatite present rare earth element (REE) patterns comparable to their counterparts in type I chondrules in ordinary chondrites. They thus likely share a similar igneous origin, likely under similar redox conditions. The mesostasis however frequently shows neg. Eu and/or Yb (and more rarely Sm) anomalies, evidently out of equilibrium with olivine and enstatite. We suggest that this reflects crystallization of oldhamite during a sulfidation event, already inferred by others, during which the mesostasis was molten, where the complementary pos. Eu and Yb anomalies exhibited by oldhamite would have possibly arisen due to a divalent state of these elements. Much of this igneous oldhamite would have been expelled from the chondrules, presumably by inertial acceleration or surface tension effects, and would have contributed to the high abundance of opaque nodules found outside them in EH chondrites. In two chondrules, olivine and enstatite exhibit neg. sloped REE patterns, which may be an extreme manifestation of a general phenomenon (possibly linked to near-liquidus partitioning) underlying the overabundance of light REE observed in most chondrule silicates relative to equilibrium predictions. The silicate phases in one of these two chondrules show complementary Eu, Yb, and Sm anomalies providing direct evidence for the postulated occurrence of the divalent state for these elements at some stage in the formation reservoir of enstatite chondrites. Our work supports the idea that the peculiarities of enstatite chondrites may not require a condensation sequence at high C/O ratios as has long been believed. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).SDS of cas: 97-09-6

The Article related to trace element chondrule enstatite chondrite, Mineralogical and Geological Chemistry: Cosmochemistry and Meteorites and other aspects.SDS of cas: 97-09-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 19, 2017, Naya, Masami; Hamano, Yoshimi; Kokado, Kenta; Sada, Kazuki published an article.Formula: C6H13NO The title of the article was Organic Reaction as a Stimulus for Polymer Phase Separation. And the article contained the following:

Mol. design of stimuli-sensitive polymers has been attracting considerable interest of chemists because of their latent ability to achieve smart materials. Heat, light, pH, and chems. have been often utilized as a stimuli-inducing polymer phase transition from solution to aggregation and vice versa. In this report, as a new trigger for lower critical solution temperature (LCST)-type polymer phase transition, we introduce organic reaction of small organic mols., not to the polymer chain itself. The addition of the reactant for the “effector”, which can interact with the polymer chain for increasing the compatibility of the polymer chain with the media, caused a polymer phase separation, due to reduction of the solvation ability of the effector to the polymer chain. In other words, decrease of the “effector” concentration induced the polymer phase separation Within our knowledge, this is the first report to connect a polymer phase separation with organic reaction dynamics. This process will be the first step for the development of artificial allosteric enzyme mimics from a combination of a simple synthetic polymer and a product or reactant in organic reactions. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Formula: C6H13NO

The Article related to organic polymer stimuli sensitive phase separation, Chemistry of Synthetic High Polymers: Organic Addition Polymerization and other aspects.Formula: C6H13NO

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 31, 2010, Mannocci, Luca; Melkko, Samu; Buller, Fabian; Molnar, Ilona; Gapian Bianke, Jean-Paul; Dumelin, Christoph E.; Scheuermann, Jorg; Neri, Dario published an article.Application In Synthesis of 2-(4-Methylbenzamido)acetic acid The title of the article was Isolation of Potent and Specific Trypsin Inhibitors from a DNA-Encoded Chemical Library. And the article contained the following:

Collections of chem. compounds, individually attached to unique DNA fragments serving as amplifiable identification bar codes, are generally referred to as “DNA-encoded chem. libraries”. Such libraries can be used for the de novo isolation of binding mols. against target proteins of interest. Here, we describe the synthesis and use of a DNA-encoded library based on benzamidine analogs, which allowed the isolation of a trypsin inhibitor with an IC50 value of 3.0 nM, thus representing a >10 000-fold potency improvement compared to the parental compound The novel trypsin inhibitor displayed an excellent selectivity toward other serine proteases. This study indicates that DNA-encoded libraries can be used for the facile “affinity maturation” of suboptimal binding compounds, thus facilitating drug development. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Application In Synthesis of 2-(4-Methylbenzamido)acetic acid

The Article related to trypsin inhibitor benzamidine derivative dna encoded library, Pharmacology: Other (All Agents and Effects Not Otherwise Assignable) and other aspects.Application In Synthesis of 2-(4-Methylbenzamido)acetic acid

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 31, 2012, Piani, Laurette; Robert, Francois; Beyssac, Olivier; Binet, Laurent; Bourot-Denise, Michele; Derenne, Sylvie; Le Guillou, Corentin; Marrocchi, Yves; Mostefaoui, Smail; Rouzaud, Jean-Noel; Thomen, Aurelien published an article.Recommanded Product: 3-Nitro-4-chlorobenzenesulfonamide The title of the article was Structure, composition, and location of organic matter in the enstatite chondrite Sahara 97096 (EH3). And the article contained the following:

The insoluble organic matter (IOM) of an unequilibrated enstatite chondrite Sahara (SAH) 97096 has been investigated using a battery of anal. techniques. As the enstatite chondrites are thought to have formed in a reduced environment at higher temperatures than carbonaceous chondrites, they constitute an interesting comparative material to test the heterogeneities of the IOM in the solar system and to constrain the processes that could affect IOM during solar system evolution. The SAH 97096 IOM is found in situ: as submicrometer grains in the network of fine-grained matrix occurring mostly around chondrules and as inclusions in metallic nodules, where the carbonaceous matter appears to be more graphitized. IOM in these two settings has very similar δ15N and δ13C; this supports the idea that graphitized inclusions in metal could be formed by metal catalytic graphitization of matrix IOM. A detailed comparison between the IOM extracted from a fresh part and a terrestrially weathered part of SAH 97096 shows the similarity between both IOM samples in spite of the high degree of mineral alteration in the latter. The isolated IOM exhibits a heterogeneous polyaromatic macromol. structure, sometimes highly graphitized, without any detectable free radicals and deuterium-heterogeneity and having mean H- and N-isotopic compositions in the range of values observed for carbonaceous chondrites. It contains some submicrometer-sized areas highly enriched in 15N (δ15N up to 1600‰). These observations reinforce the idea that the IOM found in carbonaceous chondrites is a common component widespread in the solar system. Most of the features of SAH 97096 IOM could be explained by the thermal modification of this main component. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Recommanded Product: 3-Nitro-4-chlorobenzenesulfonamide

The Article related to organic matter enstatite chondrite sahara structure composition, Mineralogical and Geological Chemistry: Cosmochemistry and Meteorites and other aspects.Recommanded Product: 3-Nitro-4-chlorobenzenesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 1, 2009, Rubin, Alan E.; Huber, Heinz; Wasson, John T. published an article.Product Details of 97-09-6 The title of the article was Possible impact-induced refractory-lithophile fractionations in EL chondrites. And the article contained the following:

Literature data show that refractory-lithophile elements in most chondrite groups are unfractionated relative to CI chondrites; the principal exception is the EL-chondrite group whose observed falls (all of which are type 6) are depleted in Ca and light REE. In contrast, literature data and our new INAA data on EL3 PCA 91020, EL3 MAC 88136 and EL4 Grein 002 show that some replicates of these samples have nearly flat REE patterns (unlike those of EL6 chondrites); other replicates exhibit fractionated REE patterns similar to those of EL6 chondrites. Petrog. examination shows that many EL6 (and some EL3 and EL4) chondrites are impact-melt breccias or contain impact-melted portions. We suggest that the same impact processes that formed these breccias and produced melt are responsible for the observed bulk compositional fractionations in refractory-lithophile elements, i.e., EL6 chondrites were produced from initially unequilibrated EL3 material. When large amounts of impact heat were deposited, plagioclase and/or oldhamite (CaS) (the major REE carriers in enstatite chondrites) may have been melted and then transported appreciable (>10 cm) distances. EL6 chondrites represent the residuum that is depleted in REE (particularly in LREE) and Ca. Unlike the case for EL chondrites, our new INAA data on ALH 84170, EET 87746 and SAH 97096 (all EH3) show some scatter but are consistent with the EH group having uniform refractory-lithophile abundances. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Product Details of 97-09-6

The Article related to impact induced refractory lithophile element fractionation el chondrite, Mineralogical and Geological Chemistry: Cosmochemistry and Meteorites and other aspects.Product Details of 97-09-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 31, 2012, Le Guillou, Corentin; Rouzaud, Jean-Noel; Bonal, Lydie; Quirico, Eric; Derenne, Sylvie; Remusat, Laurent published an article.Recommanded Product: 97-09-6 The title of the article was High resolution TEM of chondritic carbonaceous matter: metamorphic evolution and heterogeneity. And the article contained the following:

The insoluble carbonaceous matter from 12 chondrites (CI, CM, CO, CV, EH, and UOC), was characterized by high resolution transmission electron microscopy (HRTEM). Besides ubiquitous nanoglobules, the insoluble organic matter from petrol. type 1 and 2 chondrites and Semarkona (LL 3.0) is composed of a highly disordered polyaromatic component. No structural differences were observed between these IOMs, in agreement with the limited thermal metamorphism they all experienced. In chondrites of petrol. type >3.0, the evolution of the IOM is controlled by the extent of thermal metamorphism. The polyaromatic layers, shorter than 1 nm in petrol. type ≤3.0 chondrites, grow up to sizes between 5 and 10 nm in petrol. type >3.6 chondrites, contributing to the increase of the degree of structural order. In addition, we find rare, but ubiquitous onion-like carbons, which may be the product of nanodiamond graphitization. The insoluble carbonaceous matter of the enstatite chondrite Sahara 97096 (EH 3) is different from the other meteorites studied here. It is more heterogeneous and displays a high abundance of graphitized particles. This may be the result of a mixture between (1) the disordered carbon located in the matrix, and (2) catalytic graphitized phases associated with metal, potentially originating from partial melting events. The structural and nanostructural evolution are similar in all IOMs. This suggests that the structure of the accreted precursors and the parent body conditions of their secondary thermal modifications (temperature, duration, and pressure) were similar. The limited degree of organization of the most metamorphosed IOMs compared with terrestrial rocks submitted to similar temperature suggests that the conditions are not favorable to graphitization processes, due to the chem. nature of the precursor or the lack of confinement pressure. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Recommanded Product: 97-09-6

The Article related to chondritic carbonaceous matter heterogeneity metamorphic evolution hrtem, Mineralogical and Geological Chemistry: Cosmochemistry and Meteorites and other aspects.Recommanded Product: 97-09-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 15, 2016, Piani, Laurette; Marrocchi, Yves; Libourel, Guy; Tissandier, Laurent published an article.Application In Synthesis of 3-Nitro-4-chlorobenzenesulfonamide The title of the article was Magmatic sulfides in the porphyritic chondrules of EH enstatite chondrites. And the article contained the following:

The nature and distribution of sulfides within 17 porphyritic chondrules of the Sahara 97096 EH3 enstatite chondrite have been studied by backscattered electron microscopy and electron microprobe in order to investigate the role of gas-melt interactions in the chondrule sulfide formation. Troilite (FeS) is systematically present and is the most abundant sulfide within the EH3 chondrite chondrules. It is found as either poikilitically enclosed in low-Ca pyroxenes or scattered within the glassy mesostasis. Oldhamite (CaS) and niningerite [(Mg,Fe,Mn)S] are present in ≈60% of the chondrules studied. While oldhamite is preferentially present in the mesostasis, niningerite associated with silica is generally observed in contact with troilite and low-Ca pyroxene. The Sahara 97096 chondrule mesostases contain high abundances of alkali and volatile elements (average Na2O = 8.7 weight%, K2O = 0.8 weight%, Cl = 7100 ppm and S = 3700 ppm) as well as silica (average SiO2 = 62.8 weight%). The data suggests that most of the sulfides found in EH3 chondrite chondrules are magmatic minerals that formed after the dissolution of S from a volatile-rich gaseous environment into the molten chondrules. Troilite formation occurred via sulfur solubility within Fe-poor chondrule melts followed by sulfide saturation, which causes an immiscible iron sulfide liquid to sep. from the silicate melt. The FeS saturation started at the same time as or prior to the crystallization of low-Ca pyroxene during the high temperature chondrule forming event(s). Protracted gas-melt interactions under high partial pressures of S and SiO led to the formation of niningerite-silica associations via destabilization of the previously formed FeS and low-Ca pyroxene. The authors also proposed that formation of the oldhamite occurred via the sulfide saturation of Fe-poor chondrule melts at moderate S concentration due to the high d.p. and the high Na-content of the chondrule melts, which allowed the activity of CaO in the melt to be enhanced. Gas-melt interactions thus appear to be a key process that may control the mineralogy of chondrules in the different classes of chondrite. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Application In Synthesis of 3-Nitro-4-chlorobenzenesulfonamide

The Article related to magmatic sulfide porphyritic chondrule enstatite chondrite solubility inclusion, Mineralogical and Geological Chemistry: Cosmochemistry and Meteorites and other aspects.Application In Synthesis of 3-Nitro-4-chlorobenzenesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 1, 2011, Quirico, Eric; Bourot-Denise, Michele; Robin, Christophe; Montagnac, Gilles; Beck, Pierre published an article.Safety of 3-Nitro-4-chlorobenzenesulfonamide The title of the article was A reappraisal of the metamorphic history of EH3 and EL3 enstatite chondrites. And the article contained the following:

The thermal history of a series of EH3 and EL3 chondrites has been investigated by studying the degree of structural order of the organic matter (OM) located and characterized in matrix areas by Raman micro-spectroscopy. By comparison with unequilibrated ordinary chondrites (UOCs) and CO and CV carbonaceous chondrites, the following petrol. types have been assigned to various E chondrites: Sahara 97096 and Allan Hills 84206: 3.1-3.4; Allan Hills 85170 and Parsa: 3.5; Allan Hills 85119: 3.7; Qingzhen, MacAlpine Hills 88136 and MacAlpine Hills 88184: 3.6-3.7. The petrol. type of Qingzhen is consistent with the abundance of the P3 noble gas component, a sensitive tracer of the grade of thermal metamorphism. The petrol. types are qual. consistent with the abundance of fine-grained matrix for the whole series. No significant effects of shock processes on the structure of OM were observed However such processes certainly compete with thermal metamorphism and the possibility of an effect cannot be fully discarded, in particular in the less metamorphosed objects. The OM precursors accreted by the EH3 and EL3 parent bodies appear to be fairly similar to those of UOCs and CO and CV carbonaceous chondrites. Raman data however show some slight structural differences that could be partly accounted for by shock processes. The metamorphic history of EH3 and EL3 chondrites has often been described as complex, in particular regarding the combined action of shock and thermal metamorphism. Because OM maturity is mostly controlled by the temperature of peak metamorphism, it is possible to distinguish between the contributions of long duration thermal processes and that of shock processes. Comparison of the petrol. types with the closure temperatures previously derived from opaque mineral assemblages has revealed that the thermal history of EH3 and EL3 chondrites is consistent with a simple asteroidal onion shell model. Thermal metamorphism in enstatite chondrites appears to be fairly similar to that which takes place in other chondrite classes. The complex features recorded by mineralogy and petrol. and widely reported in the literature appear to be mostly controlled by shock processes. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Safety of 3-Nitro-4-chlorobenzenesulfonamide

The Article related to organic matter structural order metamorphic history enstatite chondrite meteorite, Mineralogical and Geological Chemistry: Cosmochemistry and Meteorites and other aspects.Safety of 3-Nitro-4-chlorobenzenesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Mala, S. Kumar; Priya, Antony P.; Bincy, Baby; Nazeem, P. A. published an article in 2015, the title of the article was Bioactive compounds to target anti apoptotic proteins- Bcl 2 and Bcl XL an in silico approach.Formula: C18H19NO3 And the article contains the following content:

Phytochems. from several herbaceous and spice plants have been reported to have defense properties against various diseases. Potential of some of such plants like Allium sativum, Curcuma longa, Boerhaavia diffusa, Pterocarpus marsupium and Zingiber officinale in cancer therapy has already been proved. The state of Kerala in southern India hosts large number of medicinal herbs and is also referred as a hotspot of biodiversity. The current study aimed at computational screening of potent lead mols. from ten selected medicinal plants and five spices widely used in Kerala, which are rich in biol. diversity and its traditional values. Even though, the anticancer properties of all these plants and spices were reported, their mode of action and target mols. is not well explained. Hence, the interaction of these compounds with anti-apoptotic proteins Bcl-2 and Bcl-XL are studied and discussed in this paper. The -CDOCKER energy, -CDOCKER interaction energy, Hydrogen bonds, binding energy, and complex energy were predicted through mol. docking studies. Based on binding energy and CDOCKER scores, the active components of Pterocarpus marsupium, Aegle marmelos, Pseudarthira viscida, Allium sativum, Phyllanthus amarus, Boerhaavia diffusa and Catharanthus roseus were observed to have strong interaction with both the proteins. Pharmacokinetic anal. such as absorption, solubility, BBB penetration, and toxicity were also performed for these compounds Comparative docking anal. showed higher interaction than the known inhibitors such as Obatoclax and apogossypolone. Finally, the lead mols. were screened based on their hepatotoxicity. Ten of them passed the anal. and some with high binding energy failed to do so. The lead mols. identified and their probable functional groups could be further reported to transform them as potential anti-apoptotic inhibitors. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Formula: C18H19NO3

The Article related to allium curcuma boerhaavia biol diversity, bioactive compound anti apoptotic protein india, Pharmacology: Other (All Agents and Effects Not Otherwise Assignable) and other aspects.Formula: C18H19NO3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics