Month: November 2022

Synthesis of 1,3-dienes by extrusion was written by Grainger, R. S.;Jervis, P. J.. And the article was included in Science of Synthesis in 2009.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

A review of methods to prepare 1,3-dienes by extrusion. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Stereoselective synthesis of natural (2E,4E)-dienamides and their synthetic analogs was written by Shakhmaev, R. N.;Ishbaeva, A. U.;Zorin, V. V.. And the article was included in Russian Journal of Organic Chemistry in 2012.Application In Synthesis of (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

A procedure was developed for stereoselective synthesis of a number of naturally occurring (2E,4E)-dienamides and their analogs via palladium-catalyzed reaction of (1E)-1-iodoalk-1-enes with acrylamides. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Application In Synthesis of (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Application In Synthesis of (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Viral infection as an NAD⁺ battlefield was written by Brenner, Charles. And the article was included in Nature Metabolism in 2022.Recommanded Product: 1094-61-7 The following contents are mentioned in the article:

Coronavirus replication results in expenditure of NAD (NAD⁺), the central catalyst of cellular metabolism, in the innate response to infection. Repletion of NAD⁺ levels has the potential to enhance antiviral responses. This study involved multiple reactions and reactants, such as ((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate (cas: 1094-61-7Recommanded Product: 1094-61-7).

((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate (cas: 1094-61-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Recommanded Product: 1094-61-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Viral infection as an NAD⁺ battlefield was written by Brenner, Charles. And the article was included in Nature Metabolism in 2022.COA of Formula: C11H15N2O8P The following contents are mentioned in the article:

Coronavirus replication results in expenditure of NAD (NAD⁺), the central catalyst of cellular metabolism, in the innate response to infection. Repletion of NAD⁺ levels has the potential to enhance antiviral responses. This study involved multiple reactions and reactants, such as ((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate (cas: 1094-61-7COA of Formula: C11H15N2O8P).

((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate (cas: 1094-61-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.COA of Formula: C11H15N2O8P

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Aqueous phase mono-protection of amines and amino acids as N-benzyloxycarbonyl derivatives in the presence of β-cyclodextrin was written by Kumar, V. Pavan;Reddy, M. Somi;Narender, M.;Surendra, K.;Nageswar, Y. V. D.;Rao, K. Rama. And the article was included in Tetrahedron Letters in 2006.SDS of cas: 887757-51-9 The following contents are mentioned in the article:

A simple and selective protection of amines/amino acids with Cbz-Cl was achieved in aqueous phase with catalytic amounts of β-cyclodextrin in high yields at room temperature This reaction proceeds without the formation of any byproducts and has advantages over existing methods. This study involved multiple reactions and reactants, such as Benzyl (3-hydroxypropyl)(methyl)carbamate (cas: 887757-51-9SDS of cas: 887757-51-9).

Benzyl (3-hydroxypropyl)(methyl)carbamate (cas: 887757-51-9) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.SDS of cas: 887757-51-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthesis and structure of 3-amino-4-heteroaryl-1(2H)isoquinolones was written by Nemazanyi, A. G.;Volovenko, Y. M.;Silaeva, T. A.;Kornilov, M. Yu.;Babichev, F. S.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1991.SDS of cas: 83909-69-7 The following contents are mentioned in the article:

A one-step preparation of the title compounds I (R = H, Me, CH₂Ph, Ph, 2-FC₆H₄; Ar = 2-azahetaryl) by a cyclocondensation of 2-Cl,5-(NO₂)C₆H₃CONHR with ArCH₂CN in K₂CO₃/DMF is reported. This study involved multiple reactions and reactants, such as N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7SDS of cas: 83909-69-7).

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.SDS of cas: 83909-69-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Potassium carbonate mediated unusual transformation of 2,3-dihydroquinazolinone via cascade reaction was written by Sharma, Moni;Mahar, Rohit;Shukla, Sanjeev K.;Kant, Ruchir;Chauhan, Prem M. S.. And the article was included in Tetrahedron Letters in 2013.Recommanded Product: 34489-85-5 The following contents are mentioned in the article:

An unusual potassium carbonate mediated transformation of 2,3-dihydroquinazolinone by a one-pot operation is reported under mild conditions. In addition, it is interesting to report the regioselective transformation of 3-(2-bromophenyl)-2-isopropyl-2,3-dihydroquinazolin-4(1H)-one I from compound II. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5Recommanded Product: 34489-85-5).

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Recommanded Product: 34489-85-5

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Isolation of alkamides with death receptor-enhancing activities from Piper chaba was written by Tahmina, Hoque;Toume, Kazufumi;Arai, Midori A.;Sadhu, Samir K.;Ahmed, Firoj;Ishibashi, Masami. And the article was included in Heterocycles in 2015.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

In the screening program for natural bioactive compounds that enhance the expression of death receptor 5 (DR5), activity-guided fractionation of the Piper chaba (Piperaceae) root MeOH extract led to the isolation of four alkamides (1-4). Compounds 1, 3, and 4 enhanced DR5 promoter activity while pellitorine (3) exhibited TRAIL-resistance-overcoming activity. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii was written by Choi, Eun Hyang;Choi, Ji Young;Lee, Jong Gu;Oh, Joon Seok;Kim, Dong Chun;Lee, Hee Sang;Son, Jong Keun;Ryang, Son Ae;Kim, Jeong Ah;Lee, Seung Ho. And the article was included in Saengyak Hakhoechi in 2007.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car-3-ene-2,5-dione, (-)-asarinin, (-)-sesamin, eucarvone, methyleugenol , γ-asarone, pellitorine and asarinol A by anal. of spectral data. Among them, (-)-asarinin showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 66%. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Gas-chromatographic study of anilides of aliphatic carboxylic acids was written by Sharif’yanova, L. N.;Vigdergauz, M. S.. And the article was included in Zhurnal Analiticheskoi Khimii in 1981.Recommanded Product: N-(3,4-Dichlorophenyl)octanamide The following contents are mentioned in the article:

To develop methods of gas chromatog. anal. for 16 anilides, their retention indexes on 4 stationary phases were measured, sorption thermodn. functions calculated, and equations found which connect the logarithmic retention indexes with the mol. size. The methods developed were used to control the production of N-(4-methyl-3-chlorophenyl)propionamide. This study involved multiple reactions and reactants, such as N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6Recommanded Product: N-(3,4-Dichlorophenyl)octanamide).

N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Recommanded Product: N-(3,4-Dichlorophenyl)octanamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics