Doshi, Hiren published the artcile6-Tosyl-4,5,6,7-Tetrahydrothieno[2,3-c]Pyridine-3-Carboxamide Analogues: Synthesis, Characterization, MO Calculation, and Antibacterial Activity, Category: amides-buliding-blocks, the publication is Applied Biochemistry and Biotechnology (2015), 175(3), 1700-1709, database is CAplus and MEDLINE.
A series of 6-tosyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide I (R1 = H, OH; R2 = R3 = H, Cl, OCH3; R4 = H, Cl, OCH3, OH) analogs are synthesized. These are tested for their antibacterial activity against Bacillus subtilis (abbreviated as BS), Staphylococcus aureus (abbreviated as SA), and Escherichia coli (abbreviated as EC). The synthesized compounds are able to inhibit the growth of the SA and EC. None of the compounds are effective against BS. All valence MO (abbreviated as MO) calculations with PM6 have been carried out for the mols. for which bioactivity data are available. Ciprofloxacin is taken as the standard antibiotics to compare activity with the mols. synthesized. It has been attempted to correlate the activity of the mols. with their electronic structure.
Applied Biochemistry and Biotechnology published new progress about 15029-36-4. 15029-36-4 belongs to amides-buliding-blocks, auxiliary class Nitrile,Amine,Aliphatic hydrocarbon chain,Amide, name is 2-Cyano-N-ethylacetamide, and the molecular formula is C5H8N2O, Category: amides-buliding-blocks.
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https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics