McCall, J. M. published the artcileNew approach to triaminopyrimidine N-oxides, HPLC of Formula: 15029-36-4, the publication is Journal of Organic Chemistry (1975), 40(22), 3304-6, database is CAplus and MEDLINE.
2,4,Diamino-6-(substituted amino)pyrimidine 3-oxides (I, R = H, R2 = Me, Et, Bu, n-C10H21, cyclohexyl; R = R1 = Bu, cyclohexyl; NRR1 = piperidine, 1-pyrrolidinyl) are prepared from amides NCCH2CONRR1 which are O-methylated to NCCH:C(OMe)NRR2, the products reacted with H2NCN to give NCCH2C(NRR1):NCN, and these treated in situ with NH2OH to give I. The sequential generation of the heterocycle from smaller fragments unequivocally establishes the position of the amine and N-oxide functionalities and allows ready variation of the 6-amino substituent. The three-step process proceeds in good yield and is easily performed.
Journal of Organic Chemistry published new progress about 15029-36-4. 15029-36-4 belongs to amides-buliding-blocks, auxiliary class Nitrile,Amine,Aliphatic hydrocarbon chain,Amide, name is 2-Cyano-N-ethylacetamide, and the molecular formula is C5H8N2O, HPLC of Formula: 15029-36-4.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics